Results 151 to 160 of about 30,974,445 (334)

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Response of alveolar macrophages to inhaled particulates [PDF]

, 2002
Dörger, Martina, Krombach, Fritz
core   +1 more source

Preservation of Alveolar Ridge after Preimplantation Tooth Extraction (A Review)

, 2006
The aim of the athors was to provide and represent different possibilities offered by materials for substitution of bones used after tooth extraction as a prevention of resorption of alveolar process.
R. Jurkovič, P. Stanko
core  

Sistema especialista difuso de apoio ao aprendizado do traumatismo dento-alveolar utilizando recursos multimidia [PDF]

, 1997
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoFoi desenvolvido neste trabalho um protótipo de sistema especialista difuso de apoio ao aprendizado do traumatismo dento-alveolar utilizando recursos multimidia, com ...
Fernandes, Ana Paula Soares
core  

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Effects of estrogen status in osteocyte autophagy and its relation to osteocyte viability in alveolar process of ovariectomized rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018
R. Florêncio-Silva, G. R. S. Sasso, E. Sasso-Cerri, M. Simões, P. Cerri   +4 more
semanticscholar   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

PERBANDINGAN KEADAAN TULANG ALVEOLAR ANTARA PEROKOK DAN BUKAN PEROKOK

, 2012
Perokok memiliki skor plak, kalkulus dan derajat penyakt periodontal yang lebih tinggi dibandingkan dengan bukan perokok. Dan keparahan yang terjadi justru lebih ke dalam yaitu ke arah kerusakan jaringan periodonsium, dalam hal ini tulang alveolar ...
YURNI MARDJUN, NURHAYATI SIREGAR
core  

What makes a good process model? Lessons learned from process mining

, 2012
There seems to be a never ending stream of new process modeling notations. Some of these notations are foundational and have been around for decades (e.g., Petri nets).
Aalst, WMP Wil van der, Aalst, van der, W.M.P., van der Aalst, Wil   +2 more
core   +1 more source