Results 211 to 220 of about 291,250 (334)

Alveolar Bone Segmentation Methods in Assessing the Effectiveness of Periodontal Defect Regeneration Through Machine Learning of CBCT Data: A Systematic Review. [PDF]

Int J Biomed Imaging
Mohammed M, Fernandez-Medina T, Rajashekhar M, Baker S, Jennings E.   +4 more
europepmc   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

A review of pulmonary development and neonatal interstitial lung disease in dogs and cats from a pathology perspective. [PDF]

J Vet Diagn Invest
Tsoi MF.
europepmc   +1 more source

Inhibition of Major Histocompatibility Complex II Expression and Antigen Processing in Murine Alveolar Macrophages byMycobacterium bovisBCG and the 19-Kilodalton Mycobacterial Lipoprotein

, 2004
Scott A. Fulton, Scott M. Reba, Rish K. Pai, Meghan E. Pennini, Martha Torres, Clifford V. Harding, W. Henry Boom   +6 more
openalex   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysis. [PDF]

Front Med (Lausanne)
Li B, Xia L, Liu C, Zhu Q, Chen Z.
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Segmentation-Based Multi-Class Detection and Radiographic Charting of Periodontal and Restorative Conditions on Bitewing Radiographs Using Deep Learning. [PDF]

Diagnostics (Basel)
Bayırlı AB, Kesgin B, Uytun M, Kuran A, Çitir M, Yavuz MB, Bayrakdar SK, Çelik Ö, Bayrakdar İŞ, Orhan K.   +9 more
europepmc   +1 more source

Effect of Alveolar Process and Basal Bone Features on Post-Extraction Dimensional Changes.

Couso-Queiruga, Emilio, Padial-Molina, Miguel, Galindo-Moreno, Pablo, Garaicoa-Pazmino, Carlos, Oliveira-Santos, Nicolly, Troiano, Giuseppe, Chappuis, Vivianne, Avila-Ortiz, Gustavo   +7 more
openalex   +1 more source