Results 231 to 240 of about 291,250 (334)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Acute Lung Injury Induced by Hyperbaric Oxygen or Other External Factors, with a Focus on Exosomes. [PDF]

Int J Mol Sci
Shi J, Zhao H, Yan C, Zhu P, Zhu Q, Ding W, Wang L, Zhao Y, Wang Y, Fang Y.   +9 more
europepmc   +1 more source

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

Advanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma, Qian He, Jiancheng Sun, Yiqing Chen, Hongfei Su, Ludan Zhang, Xiao He, Yuguang Wang, Changjian Xie, Zhiyong Zhang, Xin Zhou, Yuliang Zhao, Wenyan Yin   +12 more
wiley   +1 more source

Small Interfering RNA (siRNA) as a Targeted Therapy for Acute Respiratory Distress Syndrome: Evidence from Experimental Models. [PDF]

Int J Mol Sci
Kiseleva V, Vishnyakova P, Elchaninov A, Kiselev I, Sukhikh G, Fatkhudinov T.   +5 more
europepmc   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Advances in Composite Bioactive Scaffolds for Alveolar Bone Repair: Implications for Oral Surgery. [PDF]

Braz Dent J
Marampa WR, Djustiana N, Febrida R.
europepmc   +1 more source

Use of thigh fascia autograft for repairing a through-and-through soft tissue defect in the alveolar process: a clinical case

S. A. Alishlalov, S.P. Sysolyatin, Т. В. Серебров, A. S. Handzratsyan   +3 more
openalex   +2 more sources

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Signaling pathways of marine-derived natural products on lung injury: from the <i>in vivo</i> perspective. [PDF]

Front Pharmacol
Wang H, Qiu F.
europepmc   +1 more source

Raloxifene therapy inhibits osteoclastogenesis during the alveolar healing process in rats

, 2011
Eloá Rodrigues Luvizuto, Sheila S.M.D. Dias, Tetuo Okamoto, Rita Cássia Menegati Dornelles, Roberta Okamoto   +4 more
openalex   +2 more sources