Results 11 to 20 of about 9,034 (208)

Pleuroparenchymal Fibroelastosis Complicated by Pulmonary Alveolar Proteinosis After Peripheral Blood Stem Cell Transplantation. [PDF]

Respirol Case Rep
We describe a unique case of concomitant pleuroparenchymal fibroelastosis and pulmonary alveolar proteinosis following allogeneic peripheral blood stem cell transplantation for Philadelphia chromosome‐positive acute lymphoblastic leukaemia. This case illustrates the complex interplay of immune dysregulation, surfactant metabolism and chronic graft ...
Sugino K, Ono H, Saito M, Kobayashi M, Igarashib S, Hebisawa A.   +5 more
europepmc   +2 more sources

Significant but Temporary Efficacy of Statin for a Patient With Severe Autoimmune Pulmonary Alveolar Proteinosis: A Case Report. [PDF]

Respirol Case Rep
Evidence of the efficacy of statins in pulmonary alveolar proteinosis is limited and remains controversial. We report a case of severe autoimmune pulmonary alveolar proteinosis in a patient who underwent whole‐lung lavage therapy twice and achieved excellent response and remarkable clinical resolution of respiratory failure after the initiation of oral
Makino F, Shibayama K, Muto Y, Hayakawa R, Izumi K, Suzuki Y, Nagashima O, Sasaki S, Takahashi K.   +8 more
europepmc   +2 more sources

A Rare Case of Pulmonary Alveolar Proteinosis Superimposed by Severe COVID-19 Pneumonia: Case Report. [PDF]

Respirol Case Rep
This report presents a rare case of pulmonary alveolar proteinosis (PAP) in a young male who subsequently developed COVID‐19. It highlights the critical importance of integrating clinical and radiological precision in diagnosing lung diseases with overlapping imaging features and underscores the rapid deterioration observed when PAP is complicated by ...
El Mawla Z, Al Mulki J, Hassoun M.
europepmc   +2 more sources

Pulmonary Alveolar Proteinosis Complicated by Invasive <i>Streptococcus pneumoniae</i> Infection Requiring Extracorporeal Membrane Oxygenation: A Case Report. [PDF]

Acute Med Surg
A rare case of autoimmune pulmonary alveolar proteinosis complicated by invasive Streptococcus pneumoniae infection was successfully managed with veno‐venous ECMO. ECMO enabled timely whole lung lavage during recovery from septic shock, which yielded atypical yellowish‐brown fluid likely reflecting infection and led to clinical improvement.
Mizusawa U, Ohshimo S, Kikutani K, Nakamura M, Nishikimi M, Namba T, Masuka Y, Inagawa T, Shime N.   +8 more
europepmc   +2 more sources

Rapid Serological Detection of Anti-GM-CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test. [PDF]

Respirology
We developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. See related editorial ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential ...
Narita C, Shima K, Sekiguchi JI, Ozeki Y, Akiwa M, Koike S, Yuki S, Akasaka K, Kikuchi T, Kitamura N, Nakata K.   +10 more
europepmc   +2 more sources

CD40LG-associated X-linked Hyper-IgM Syndrome (XHIGM) with pulmonary alveolar proteinosis: a case report

BMC Pediatrics, 2023
Background D40LG-associated X-linked hyper-IgM syndrome with pulmonary alveolar proteinosis has rarely been reported, and its genotype-phenotypic correlation remains elusive. Case presentation We describe a five-month-old boy with CD40LG mutation (c.516T 
Hong-bo Xu, Mao-qiang Tian, Yong-hua Bai, Xiao Ran, Lei Li, Yan Chen   +5 more
doaj   +1 more source

A Hereditary Pulmonary Alveolar Proteinosis Caused by a Novel Hemizygous Variation of the CSF2RA Gene Case Report and Literature Review. [PDF]

Mol Genet Genomic Med
This paper describe a 3‐year‐old girl with Turner syndrome who presented with recurrent cough and dyspnea and was diagnosed with hereditary PAP. Genetic analysis revealed a novel hemizygous mutation in the CSF2RA gene (NM_000402.4:c.200_204del, p.Asn67SerfsTer8), which was confirmed as a de novo pathogenic variant and had not been reported previously ...
Chen Q, Zhang S, Zhu X, Zhu Y, Chen J, Chen H, Xiao G.   +6 more
europepmc   +2 more sources

Autoimmune pulmonary alveolar proteinosis successfully treated with lung lavage in an adolescent patient: a case report

Journal of Medical Case Reports, 2021
Background Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pediatric age group, the vast majority ...
Abdalla Mohmed Alasiri, Reem Abdullah Alasbali, Meaad Ali Alaqil, Aishah Marei Alahmari, Nouf Dagash Alshamrani, Rabab Nasir Badri   +5 more
doaj   +1 more source

Pulmonary alveolar proteinosis [PDF]

Respirology, 2020
ABSTRACTPAP is an ultra‐rare disease in which surfactant components, that impair gas exchange, accumulate in the alveolae. There are three types of PAP. The most frequent form, primary PAP, includes autoimmune PAP which accounts for over 90% of all PAP, defined by the presence of circulating anti‐GM‐CSF antibodies.
Jouneau, Stéphane, Menard, Cedric, Lederlin, Mathieu   +2 more
openaire   +3 more sources

Pulmonary Alveolar Proteinosis: Case Report

Архивъ внутренней медицины, 2020
Pulmonary alveolar proteinosis is a rare disease of the lungs due to abnormal surfactant metabolism with accumulation of pathological protein lipid substance in the lumen of alveoli.Presented case of idiopathic alveolar proteinosis is characterized by ...
N. A. Karoli, E. E. Arhangelskaja, O. T. Zarmanbetova   +2 more
doaj   +1 more source