Long-term follow-up and treatment of congenital alveolar proteinosis
BMC Pediatrics, 2011 Background Clinical presentation, diagnosis, management and outcome of molecularly defined congenital pulmonary alveolar proteinosis (PAP) due to mutations in the GM-CSF receptor are not well known.
Muensterer Oliver J +14 more
doaj +1 more source
Lung Lavage Cell Profiles in Diffuse Lung Disease [PDF]
, 2010 The standard armamentarium of tests that are used by pulmonologist are laboratory tests, pulmonary function tests, different radiological techniques (conventional chest-X rays, HRCT scans, etc) and pathohistological analyses of biopsies.
Silvana Smojver-Ježek +1 more
core +1 more source
Epithelial–Mesenchymal Transition in Human Alveolar Cells Exposed to Indium Chloride
Journal of Applied Toxicology, Volume 45, Issue 11, Page 2353-2362, November 2025.ABSTRACT For workers in the industry, occupational exposure to indium compounds induces pulmonary disorders, such as interstitial pneumonia. Moreover, lung cancer has been reported in both humans and rodents exposed to indium compounds by inhalation. However, the biological mechanism underlying indium‐induced disorders is poorly understood.
Eiki Kimura +3 more
wiley +1 more source
Neumonía lipídica endógena en 2 gatos de raza Persa [PDF]
, 2006 En este trabajo se describen dos casos de neumonía lipídica endógena en dos gatos de raza persa. En ambos se llegó al diagnóstico por necropsia. Se describen los tratamientos aplicados y se discute el diagnóstico y tratamientos de elección, así como ...
Avellaneda, Ana, Font Utset, Artur
core
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis [PDF]
, 2015 Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either protection or morbidity are not completely understood. We show that in response to lung infection,
Ali, Muhammad +13 more
core +1 more source
Early IL‐1 Inhibition in Still's Disease: A Window of Opportunity for Improving Outcomes
ACR Open Rheumatology, Volume 7, Issue 10, October 2025.Objective Still's disease is a complex, multisystemic disorder requiring prompt diagnosis and treatment. This study provides a general assessment of a Still's disease cohort aiming to evaluate the efficacy of early intervention with interleukin‐1 inhibitors (IL‐1i) in achieving clinical inactive disease (CID) and reducing glucocorticoid use in patients
Sara Bindoli +5 more
wiley +1 more source
Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework [PDF]
, 2017 Background The accumulation of MWCNTs in the lung environment leads to inflammation and the development of disease similar to pulmonary fibrosis in rodents.
Banville, Allyson +8 more
core +1 more source
The Paradox of Metachronous Lipoid Pneumonia
Respirology Case Reports, Volume 13, Issue 9, September 2025.This is a case of recurrent exogenous lipoid pneumonia in a single patient caused by multiple unrelated substances. This case underscores the diagnostic value of radiologic patterns, the significance of meticulous exposure history, and the necessity of contemplating alternative aetiologies in patients with new infiltrates during cancer therapy ...
Haruki Kobayashi
wiley +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source
Niche signals and transcription factors involved in tissue-resident macrophage development [PDF]
, 2018 Tissue-resident macrophages form an essential part of the first line of defense in all tissues of the body. Next to their immunological role, they play an important role in maintaining tissue homeostasis. Recently, it was shown that they are primarily of
Bonnardel, Johnny +2 more
core +2 more sources