Results 51 to 60 of about 7,740 (174)

Can Response Outcomes Predict Survival in Paediatric Patients Receiving Treatment for Relapsed and Refractory Rhabdomyosarcoma? Results From the Living‐REFoRMS Systematic Review

International Journal of Cancer, Volume 159, Issue 4, Page 997-1004, 15 August 2026.
Although existing research suggests a limited relationship between survival outcomes and radiological response rates in children with newly diagnosed rhabdomyosarcoma, there is little evidence in the relapsed/refractory setting. Using aggregate data collected from the Living‐REFoRMS dataset of early‐phase trials, the authors established that ...
Preethi Muthukumar, Lucy Shepherd, Sumayya Anwer, Connor Evans, Jessica E. Morgan   +4 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Alveolar Rhabdomyosarcoma of the Laryngohypopharynx: A Case Report

Cancer Biology & Medicine, 2010
Rhabdomyosarcoma is one of the most commonly seen soft-tissuesarcomas in children and teenagers, approximately accounting forhalf of all soft-tissue sarcomas[1]. The tumor is usually found in head and neck, four limbs and urogenital system.
Da-wei LI, Jin XIE, Pin DONG
doaj   +1 more source

Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. [PDF]

PLoS Genetics, 2014
Rhabdomyosarcoma is the most commonly occurring soft-tissue sarcoma in childhood. Most rhabdomyosarcoma falls into one of two biologically distinct subgroups represented by alveolar or embryonal histology.
Ken Kikuchi, Simone Hettmer, M Imran Aslam, Joel E Michalek, Wolfram Laub, Breelyn A Wilky, David M Loeb, Brian P Rubin, Amy J Wagers, Charles Keller   +9 more
doaj   +1 more source

Paratesticular Embryonal Rhabdomyosarcoma Masquerading as Epididymitis: A Diagnostic Challenge in Adolescents

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Paratesticular rhabdomyosarcoma is a rare malignancy in children and adolescents that frequently presents diagnostic challenges when mimicking benign inflammatory conditions. We report the case of a 14‐year‐old previously healthy male who presented with acute right scrotal pain and swelling initially diagnosed as epididymo‐orchitis.
Saif Khaled Abdalhadi Azzam, Lina Barhoum Barhoum, Ammir Abuzahra, Alaa Alazzeh, Khader Hassouneh, Nour Aldin K. Fakhory, Mohd Othman Lafi, M. I. Jawabreh Issa, Ibrahim Alzatari, Hamza Zughaier   +9 more
wiley   +1 more source

Alveolar Rhabdomyosarcoma of Oral Cavity – A Rare Case [PDF]

Al Ameen Journal of Medical Sciences, 2010
Rhabdomyosarcomas are the malignant tumors of the striated skeletal muscles. Rhabdomyosarcomas are the most common soft tissue sarcoma of the children, adolescents and young adults. An eleven year old boy who presented with a painless progressive lump in
Ravi Batra, D.O.Gupta, Pooja Sharma, Pradeep Bokariya   +3 more
doaj  

The impact of whole lung irradiation in lung metastatic rhabdomyosarcoma: A pooled analysis of two European trials and one European registry

Cancer, Volume 132, Issue 15, 1 August 2026.
ABSTRACT Background Lung metastases in patients with metastatic rhabdomyosarcoma (RMS) have not been treated uniformly across Europe. This provides comparison of the impact of whole lung irradiation (WLI). Methods Lung‐metastatic patients included in the Cooperative Weichteilsarkom Studiengruppe‐IV 2002, European Pediatric Soft Tissue Sarcoma Study ...
Amadeus T. Heinz, Philip Heesen, Johannes H. M. Merks, Véronique Minard‐Colin, Martin Ebinger, Alison L. Cameron, Semi Harrabi, Henry Mandeville, Reineke A. Schoot, Jörg Fuchs, Gabriela Guillen, Ewa Koscielniak, Julia C. Chisholm, Monika Sparber‐Sauer, Gianni Bisogno   +14 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Nonparameningeal alveolar rhabdomyosarcoma, with cytohistological features: A case report

Indian Journal of Pathology and Microbiology, 2019
Rhabdomyosarcoma (RMS) is a tumor arising from primitive mesenchymal cell with tendency for myogenesis. WHO classification categorizes this entity as embryonal, alveolar, spindle cell/sclerosing, and pleomorphic subtypes removing botryoid as a separate ...
Neelam Sood, Arun K Haldia
doaj   +1 more source

A subset of high‐grade sarcomas with myogenic differentiation are associated with recurrent FGFR fusions

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Recurrent fusions involving FGFR1‐4 genes have been previously described in rare subsets of mostly benign chondroid and mesenchymal neoplasms involving bone and soft tissue. However, a more comprehensive analysis of sarcomas associated with FGFR fusions, including their incidence and histotypes, has not been performed.
Maximus CF Yeung, Carla Saoud, Sarah Chiang, Meera Hameed, Cristina R Antonescu   +4 more
wiley   +1 more source