Results 281 to 290 of about 472,310 (340)

The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross‐Sectional Studies of Schizophrenia and the General UK Population

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart, Sophie E. Legge, Eilidh Fenner, Antonio F. Pardiñas, Grace Woolway, Amy J. Lynham, Valentina Escott‐Price, Jeremy Hall, Lawrence Wilkinson, Peter Holmans, Michael C. O'Donovan, Michael J. Owen, James T.R. Walters   +12 more
wiley   +1 more source

Bacteria in the brain: do they have a role in the pathogenesis of Alzheimer's disease? [PDF]

Curr Opin Psychiatry
Bhattacharya A, Shepherd C, El-Assaad F, Mather KA.   +3 more
europepmc   +1 more source

Diglycerides of Natural Phenols and Organic Acids for Enhanced Biological Activities

Asian Journal of Organic Chemistry, EarlyView.
Diglycerides of natural organic acids and phenols were synthesized regio‐selectively. Diglycerides are structurally similar to cell membranes and are expected to exhibit cell affinity and permeability. The flexible glycerol linkers allow the diglycerides to exhibit not only the physiological activities of each constituent organic acid but also the ...
Jisu Hong, Seunghyo Han, Huisu Yeo, Chanyoung Boo, Hyein Kim, Eunbi Kim, Boram Lim, Yeon Jeong Jo, Ji‐Seon Hyun, Nam Ho Lee, Sangho Koo   +10 more
wiley   +1 more source

Biomarker changes associated with fornix deep brain stimulation in Alzheimer's disease. [PDF]

Alzheimers Dement
Germann J, Amaral RSC, Tomaszczyk J, Yamamoto K, Elias GJB, Gouveia FV, Vasilevskaya A, Taghdiri F, Devenyi GA, Sankar T, Leoutsakos JM, Munro CA, Rosenberg PB, Lyketsos CG, Oh ES, Anderson WS, Mari Z, Fosdick L, Drake KE, Targum SD, Pendergrass JC, Burke A, Salloway S, Asaad WF, Ponce FA, Sabbagh M, Wolk DA, Baltuch G, Okun MS, Foote KD, Giacobbe P, McAndrews MP, Tang-Wai DF, Smith GS, Tartaglia MC, Chakravarty MM, Lozano AM, Alzheimer's Disease Neuroimaging Initiative.   +37 more
europepmc   +1 more source

Reversal of Regioselectivity in the Nucleophilic Fluorination of 1,2‐Dimesylate with Potassium Fluoride and 18‐Crown‐6

Asian Journal of Organic Chemistry, EarlyView.
An unexpected regio‐ and chemoselectivity was found for nucleophilic fluorination of a terminal vicinal dimesylate. Theoretical calculations were used to explain the origin of this effect. Abstract The control of chemoselectivity and regioselectivity in chemical reactions is a crucial area of research, focused on achieving the desired product with high
Eloah P. Ávila, Karla L. Lopes, Mauro V. de Almeida, Josefredo R. Pliego   +3 more
wiley   +1 more source

Why testing and diagnosis for Alzheimer's disease are mission critical. [PDF]

Alzheimers Dement (N Y)
Beasley BW.
europepmc   +1 more source

Research advances in dysphagia animal models

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai, Keling Cheng, Nannan Zhang, Yunfang Chen, Jun Ni, Zhiyong Wang   +5 more
wiley   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 1: Principles and Practice

Annals of Neurology, EarlyView.
Artificial intelligence (AI) is rapidly transforming healthcare, yet it often remains opaque to clinicians, scientists, and patients alike. This review, part 1 of a 3‐part series, provides neurologists and neuroscientists with a foundational understanding of AI's key concepts, terminology, and applications.
Matthew Rizzo, Jeffrey D. Dawson
wiley   +1 more source