Results 121 to 130 of about 748,400 (282)
La inserción de América Latina en las cadenas globales de valor [PDF]
, 2010 Se examina la integración de firmas latinoamericanas al modelo de Cadenas Globales de Valor (CGV), analizando la formación de cadenas lideradas por firmas de los países de América Latina y evaluando su impacto sobre el comercio, la inversión y el ...
Garrido Noguera, Celso +4 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nuevo registro de un cachalote (Physeter macrocephalus) varado y una revisión de varamientos en las costas de Argentina continental [PDF]
, 2011 Presentamos un nuevo registro de un cachalote, con notas sobre la dieta, la determinación de edad y la presencia de parásitos, junto con una revisión de los varamientos a lo largo de toda la costa continental argentina.
Crespo, Enrique Alberto +8 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Orchidaceae Austro-americanae, III
Lilloa, 2021 Una revisión de orquídeas de varias regiones de América del Sur. Se proponen un nuevo género, cuatro nuevas especies y un nuevo nombre. Dos de las nuevas especies son de Venezuela y dos de Colombia.
Louis Otho Williams
doaj
Measurement of physical activity and sedentary behavior in national health surveys, South America. [PDF]
Rev Panam Salud Publica, 2022 Silva DR +13 more
europepmc +1 more source
“PODER, GOBIERNO Y ESTRATEGIAS EN LAS UNIVERSIDADES DE AMÉRICA DEL SUR” [PDF]
, 2005 En este texto nos interesa formular algunas reflexiones, opiniones y notas sobre la necesidad de revisar la relación entre investigación y transferencia social y compartir una voluntad de soñar, pensar y fundamentalmente accionar sobre la realidad desde
Cacopardo, Fernando +2 more
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source