Results 51 to 60 of about 20,884,610 (254)
, 2020 Mensaje de Alicia Bárcena, Secretaria Ejecutiva de la CEPAL, al Foro de Personas Defensoras del Medio Ambiente en América del Sur (4-5 de noviembre de 2020).0:00'00"-0:07'35": Plano Medio de la Secretaria Ejecutiva de la CEPAL, Alicia Bárcena, mientras ...
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Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Espacio y Desarrollo, 2001 En la última década y como consecuencia del debate abierto en torno al MERCOSUR se ha reactualizado el interés por el estudio de la recurrente tendencia de los países latinoamericanos hacia la conformación de unidades políticas o económicas, más amplias ...
Beatriz R. Solveira
doaj
AVALIAÇÃO E ACREDITAÇÃO DA EDUCAÇÃO SUPERIOR NA AMÉRICA LATINA: OS CASOS DA ARGENTINA E DO BRASIL NO CONTEXTO DO MERCOSUL [PDF]
, 2009 O artigo recupera o contexto de surgimento da avaliação da educação superior na América Latina e analisa os sistemas de avaliação e acreditação da educação superior na Argentina e no Brasil. Focaliza a análise em aspectos como: as características de cada
LAGORIA, SILVANA LORENA +1 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
La gran recesión y el retorno de la política en América del Sur
Iberoamericana. América Latina - España - Portugal, 2014 La concurrencia actual de escenarios políticos y económicos ha permitido que América Latina pudiera adoptar una estrategia para afrontar la crisis internacional que difiere sustancialmente de aquélla adoptada en otras latitudes, manteniendo en el tiempo ...
Pablo Trucco, Diana Tussie
doaj +1 more source
Clusters of rare disorders and congenital anomalies in South America. [PDF]
Rev Panam Salud Publica, 2023 Cardoso-Dos-Santos AC +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source