Results 41 to 50 of about 16,478 (220)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

ENTRE O TRÁFICO HUMANO E A OPÇÃO DA MOBILIDADE SOCIAL: OS IMIGRANTES BOLIVIANOS NA CIDADE DE SÃO PAULO

Cadernos Prolam/USP, 2006
A proposta deste artigo é examinar as singularidades e os desafios enfrentados pela comunidade boliviana que, na busca de melhores condições de vida, submete-se ao tráfico humano e ao trabalho indocumentado na Região Metropolitana de São Paulo.
Maria Cristina Cacciamali
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

CRÉDITO À EXPORTAÇÃO NA AMÉRICA LATINA E AS REGRAS SOBRE SUBSÍDIOS DA OMC: ANÁLISE DE CONFORMIDADE E DE ALTERNATIVAS

Cadernos Prolam/USP, 2011
O presente trabalho investiga a compatibilidade do maior programa de crédito para exportação do governo brasileiro, o BNDES-EXIM, e de programas similares da Argentina e do Chile, com as regras da OMC sobre subsídios.
José Guilherme Moreno Caiado
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

MONEY AS A TOTAL SOCIAL FACT IN ARGENTINEAN 2001/02 CRISIS AND IN ITS RESOLUTION

Cadernos Prolam/USP, 2011
This paper opposes to the institutional explanations for sudden reversals of expectations, as was the case in the Argentinean crisis 2001/2002, an analysis revealing a crisis of the trust set in national currency, so conceived as total social fact. Based
Jaime Marques Pereira
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A aviação comercial na América do Sul: um estudo comparativo entre a influência alemã e norte-americana na região (1919-1945)

Estudos Ibero Americanos, 2003
O presente estudo enfoca o desenvolvimento da aviação na América do Sul entre 1919 e 1945. A disputa entre as potências pela abertura de novos mercados e áreas de influência política e cultural marcaram esse período. O artigo propõe um estudo comparativo
Fay, Cláudia Musa
doaj  

LOS SISTEMAS DE RELACIONES LABORALES. ANÁLISIS DESDE EL CONO SUR DE AMÉRICA LATINA

Cadernos Prolam/USP, 2011
El objetivo de este documento es construir un marco teórico metodológico para el análisis de los Sistemas de Relaciones Laborales teniendo en cuenta las particularidades de la región.
Jorge Notaro
doaj   +1 more source