Results 111 to 120 of about 384,371 (268)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Spreading further: the first record of the alien bivalve Theora lubrica in the Southwestern Atlantic Ocean

Frontiers in Marine Science
Biological invasions are globally recognized as one of the main drivers of biodiversity loss. Over the past four decades, there has been significant progress in understanding the mechanisms of alien species introduction into marine and estuarine ...
Fabrizio Marcondes Machado, Cristiane Midori Suga, Fabio Kiyoshi Camara Onodera, Mariana Sousa Melo, Thais Viti, Vilma Maria Cavinatto, Ana Carolina da Rocha Lammardo, Carolina Yumi Yonamine, Regina Sawaia Sáfadi, Luis Antonio Nogueira-Junior, Luiz Fernando Maciel Oliva   +10 more
doaj   +1 more source

Uncovering the impact of COVID-19 on the place of death of cancer patients in South America. [PDF]

Cad Saude Publica, 2023
Durán D, Anyosa RC, Nicolau B, Kaufman JS.   +3 more
europepmc   +1 more source

A ALBA enquanto ferramenta de enfrentamento ao poderio do norte: continuidades e rupturas da política exterior Venezuelana para América Central e Caribe [PDF]

, 2017
A II Semana Acadêmica de Relações Internacionais foi realizada em novembro de 2017, na Universidade Federal da Integração Latino-Americana (UNILA), nas dependências do campus do Parque Tecnológico de Itaipu (PTI) e do campus Jardim Universitário (JU)A ...
Simioni, Amanda Orguim
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Produção de carvão vegetal e conversão produtiva de assentados da reforma agrária. [PDF]

, 2015
Neste trabalho, apresenta-se o processo de transição agroecológica representado pelo abandono da atividade carvoeira e a conversão para a produção orgânica de hortaliças por famílias participantes de um projeto desenvolvido pela Embrapa em parceria com o
COSTA, J. R., SILVA, A. M., SOARES, J. E. C.   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Systematic literature review of primary and secondary cervical cancer prevention programs in South America. [PDF]

Rev Panam Salud Publica, 2023
Gomes MLS, Moura NDS, Magalhães LC, da Silva RR, Silva BGS, Rodrigues IR, Sales LBF, Oriá MOB.   +7 more
europepmc   +1 more source

Onde erramos: historiografia e auto-crítica das guerrilhas do Cone Sul [PDF]

, 2016
“Anais da 2a Semana Acadêmica de Ciência Política e Sociologia: Violência e Democracia na América Latina.” - 09, 10 e 11 de Novembro de 2016. Realização: Curso de Graduação em Ciência Política e Sociologia - Sociedade, Estado e Política na América Latina.
Cruz, Geison Siqueira Tavares da
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source