Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Uncovering the impact of COVID-19 on the place of death of cancer patients in South America. [PDF]
Cad Saude Publica, 2023 Durán D +3 more
europepmc +1 more source
Reforms of constitutions in South America [PDF]
, 2008 O artigo trata das mudanças políticas na América do Sul. Nesse sentido, aborda a transformação do Estado via reforma constitucional. _________________________________________________________________________________________ ABSTRACTThe article ...
Cervo, Amado Luiz
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ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Estrutura Microfísica das Nuvens em Diferentes Ecossistemas da América do Sul. [PDF]
, 2009 Clouds directly affect meteorological conditions of the planet, by interacting with electromagnetic radiation from the sun, the earth’s surface and the atmosphere.
Bruno Muniz Duarte +1 more
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Systematic literature review of primary and secondary cervical cancer prevention programs in South America. [PDF]
Rev Panam Salud Publica, 2023 Gomes MLS +7 more
europepmc +1 more source
Conservação ambiental forte alcançada através de sistemas agroflorestais multiestratificados: 2 - restauração de paisagens degradadas por meio de agroflorestas. [PDF]
, 2015 Foi avaliada a sustentabilidade ambiental em nível da paisagem de práticas de sistemas agroflorestais multiestratificados na região do Vale do Ribeira, SP e PR, na escala da unidade de produção agrícola familiar, baseando-se nos resultados de várias ...
AMARAL-SILVA, J. +5 more
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Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Stigma experienced by people with mental illness in South America: an integrative review. [PDF]
Rev Cuid, 2022 Hernandez-Fernandes RH +5 more
europepmc +1 more source