Results 71 to 80 of about 575,735 (293)

O Brasil e a distante América do Sul

Revista de História, 2001
Este artigo discute a elaboração de um discurso político original, no Brasil do século XIX, que fundou uma certa interpretação brasileira sobre o mundo hispano-americano, contribuindo para a constituição de um imaginário sobre a outra América, que a ...
Maria Ligia Coelho Prado
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

SISTEMA TRIBUTARIO Y EL PROBLEMA FEDERATIVO: LA EVOLUCIÓN DEL CASO BRASILEÑO

Cadernos Prolam/USP, 2002
El presente artículo tiene por objetivo caracterizar la evolución de los aspectos tributarios de las relaciones intergubernamentales brasileñas. Buscando establecer taxonomías relativas tanto a las distintas posibilidades de evolución histórica de la ...
Amaury Patrick Gremaud
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Seasonal variation in the number of captures of Artibeus lituratus (Olfers, 1818) and Sturnira lilium (E. Geoffroy, 1810) (Chiroptera: Phyllostomidae) in the upper strata of an Atlantic Forest remnant in southern Brazil

Biotemas, 2014
This study aimed to analyze the occurrence of seasonal variations in the number of captures of Artibeus lituratus and Sturnira lilium in the upper strata of an Atlantic Forest remnant in southern Brazil. It was conducted in the town of Pedras Grandes, in
Fernando Carvalho, Marta Elena Fabián, João Odair Menegheti   +2 more
doaj  

POLITICA INDUSTRIAL Y PEQUEÑAS Y MEDIANAS EMPRESAS: EL CASO ARGENTINO

Cadernos Prolam/USP, 2009
Este trabajo examina el caso de las políticas argentinas para las pequeñas y medianas empresas (PyMEs). Se trata de políticas a las que se les reconoce la capacidad de suplir funciones de fomento y de coordinación que los automatismos del mercado no ...
Marina Schenkel
doaj   +1 more source

Regionalismo e desenvolvimento na América do Sul

Revista Debates, 2018
O objetivo do presente trabalho é discutir os diferentes modos de entender o desenvolvimento periférico que tiveram expressão nas variadas experiências de integração na América do Sul a partir de meados do século XX.
Leonardo Granato, I. R. Batista
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

ENTRE O TRÁFICO HUMANO E A OPÇÃO DA MOBILIDADE SOCIAL: OS IMIGRANTES BOLIVIANOS NA CIDADE DE SÃO PAULO

Cadernos Prolam/USP, 2006
A proposta deste artigo é examinar as singularidades e os desafios enfrentados pela comunidade boliviana que, na busca de melhores condições de vida, submete-se ao tráfico humano e ao trabalho indocumentado na Região Metropolitana de São Paulo.
Maria Cristina Cacciamali
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source