Results 161 to 170 of about 3,579,030 (363)

Chikungunya en las Américas: Preparación, vigilancia y alerta en Chile [PDF]

, 2014
Diego E Clouet-Huerta, Patricio Alfaro-Toloza, Alfonso J. Rodríguez‐Morales   +2 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Zika virus in the Americas: Early epidemiological and genetic findings

Science, 2016
N. Faria, R. S. Azevedo, M. Kraemer, R. Souza, M. S. Cunha, S. Hill, J. Thézé, M. Bonsall, T. Bowden, I. Rissanen, I. Rocco, J. Nogueira, A. Maeda, F. G. Vasami, Fernando L L Macedo, A. Suzuki, S. Rodrigues, A. C. Cruz, B. Nunes, D. B. Medeiros, D. S. G. Rodrigues, Alice Louize Nunes Queiroz, Eliana V. P. Silva, D. F. Henriques, E. S. Travassos da Rosa, C. S. de Oliveira, L. C. Martins, H. B. Vasconcelos, L. M. Casseb, D. B. Simith, J. Messina, L. Abade, J. Lourenço, L. Alcântara, M. Lima, M. Giovanetti, Simon Iain Hay, Rodrigo Santos de Oliveira, P. Lemos, L. Oliveira, C. P. S. de Lima, S. P. da Silva, J. M. Vasconcelos, L. Franco, J. Cardoso, J. L. S. G. Vianez-Júnior, D. Mir, G. Bello, E. Delatorre, K. Khan, Marisa Creatore, G. Coelho, Wanderson K. de Oliveira, R. Tesh, O. Pybus, M. Nunes, P. Vasconcelos   +56 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Well-being and the Complexity of Poverty: A Subjective Well-being Approach [PDF]

socioeconomic indicators, subjective well-being, happiness ...
Rojas, Mariano
core  

Encuentros urbanos [PDF]

, 2014
Trabajo de gradoEsta monografía trata a cerca de la aplicación de conceptos y normativa para el desarrollo de un proyecto de Renovación Urbana, Conservación y Desarrollo, ubicado entre la Av. Américas, Av. Ciudad de Quito y Av.
Laiton-Maldonado, Jenifer, Dayane
core  

Establishment and cryptic transmission of Zika virus in Brazil and the Americas

Nature, 2017
Nuno R. Faria, J. Quick, Ingra Morales, J. Thézé, J. D. Jesus, M. Giovanetti, M. Kraemer, S. Hill, Allison Black, A. C. Costa, L. Franco, S. P. Silva, Chiej-Hsi Wu, Jayna Ragwhani, S. Cauchemez, L. Plessis, M. Verotti, W. Oliveira, E. H. Carmo, G. Coelho, A. Santelli, L. Vinhal, C. Henriques, J. Simpson, M. Loose, K. Andersen, N. Grubaugh, S. Somasekar, C. Chiu, L. Lewis-Ximenez, S. Baylis, A. Chieppe, S. F. Aguiar, Carlos A S Fernandes, P. Lemos, B. S. Nascimento, H. Monteiro, I. Siqueira, Maria G L Queiroz, T. R. Souza, J. F. Bezerra, Marta Lemos, G. Pereira, D. Teixeira, L. C. Moura, R. Dhalia, R. F. Franca, T. Magalhaes, E. Marques, G. Wallau, M. C. Lima, V. Nascimento, E. Cerqueira, M. Lima, D. L. Mascarenhas, José Neto, A. Levin, T. Mendoza, S. Fonseca, M. Mendes-Correa, F. Milagres, A. Segurado, E. Holmes, A. Rambaut, T. Bedford, Marcio Nunes Roberto Teixeira, E. Sabino, L. Alcântara, N. Loman, O. Pybus   +69 more
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

UNASUR: Developments in the Defense Area [PDF]

, 2013
The article summarizes the last developments in South America towards a common defense area, referring to the history and origins of the Union of South American Nations (UNASUR).Fil: Gil, Luciana Victoria. Universidad de Buenos Aires; Argentina.
Gil, Luciana Victoria
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source