Results 171 to 180 of about 3,579,030 (363)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

¿Debemos esperar una mayor expansión de distintos Arbovirus en las Américas?

open access: diamond, 2017
Andrés Mauricio Patiño-Barbosa   +1 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Análise cienciométrica da produção científica sobre turismo alternativo nas Américas entre 1973 a 2017

open access: green, 2021
Heloise Michelle Nunes Medeiros   +2 more
openalex   +2 more sources

Os Jesuítas nas Américas: "A República dos Guaranis" [PDF]

open access: yes, 2013
Para este trabalho elegemos um estudo sobre uma "experiência jesuíta" junto dos Guaranis, que designamos de "A República dos Guaranis". Trata-se de um processo histórico complexo que teve início no século XVII, sob o impacto da Contra-Reforma, e terminou
Manso, Maria de Deus Beites   +1 more
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

The isolation of America : the ideological and poetic purpose of misrepresentation [PDF]

open access: yes, 2001
El presente artículo pretende explicar por qué el dramaturgo preeminente del Siglo de Oro, Lope de Vega, se refiere repetidas veces a una colonia imperial americana, el Brasil, como una isla en su comedia. El Brasil restituido. Se aclara que el aparente
Shannon, Robert M.
core   +3 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

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