Results 151 to 160 of about 2,279,293 (256)

MicroRNAs as Biomarkers for Adenomyosis: A Systematic Review. [PDF]

Biomedicines
Buehler P, Vidal A, Vaineau C, Karrer T, Mueller M.   +4 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Revision of calcium and scandium abundances in Am stars based on NLTE calculations and comparison with diffusion stellar evolution models [PDF]

The homogeneous data sets for the calcium and scandium abundances accounting for departures from LTE were obtained for a sample of 54 metallic-line (Am) stars.
Fadeyev, Yu. A., Mashonkina, L. I.
core  

A Comparison of Juvenile and Adult Sunflower Sea Star Transcriptomic Responses to Challenge With Sea Star Wasting Disease Tissue Homogenates. [PDF]

Ecol Evol
Crandall G, Gehman AM, Davis K, Prentice MB, Harvell D, White SJ, Hershberger P, Roberts S.   +7 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Assessment of Medicare Advantage Stars Measures: Impact on Kidney Care Quality and Future Opportunities. [PDF]

J Am Soc Nephrol
Le D, Ahearn L, Wilk AS, Udani S, Hall R, El Shamy O, Bieber S, Cervantes L, Chen CH, Gould E, Jain G, Kshirsagar AV, Lau WL, Mohan S, Rivara MB, Aggarwal V, Tummalapalli SL, Seo-Mayer P, Mendu ML, American Society of Nephrology Quality Committee.   +19 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Comparative safety and effectiveness of midline catheters vs. peripherally inserted central catheters: a systematic review and meta-analysis. [PDF]

Front Cardiovasc Med
Aljameie M, Ahmed Shimal A, Mahmoud MH, Abbas OF, Oudah AM, Ahmed MJ, Hamzah KA, Mansour A, Abdullatif Abdulqader W, Aljubori E, Mohammed G, Alkhateeb FS, El-Ramly TA, Al-Sagban A, Graham H, Musri MC.   +15 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source