Results 41 to 50 of about 6,263 (187)
Pupillometric analysis for assessment of gene therapy in Leber Congenital Amaurosis patients [PDF]
, 2012 Background: Objective techniques to assess the amelioration of vision in patients with impaired visual function are needed to standardize efficacy assessment in gene therapy trials for ocular diseases.
Melillo Paolo +19 more
core +1 more source
Case Reports in Rheumatology, 2019 Giant cell arteritis, a large vessel vasculitis is characterized by headache, visual impairment, constitutional symptoms, and increased inflammatory markers. Visual involvement in giant cell arteritis ranges from amaurosis fugax to permanent visual loss,
Anne D. D. Joseph +3 more
doaj +1 more source
Retinal Arterial Obstruction-still Remains an Enigma [PDF]
Journal of Clinical and Diagnostic Research, 2014 Retinal artery obstruction is an ocular emergency which usually carries a poor visual prognosis. Restoration of fruitful vision depends on the underlying cause and the immediate start of treatment.
Anupama Kakhandaki +3 more
doaj +1 more source
Annals of Neurology, Volume 99, Issue 3, Page 705-712, March 2026.Objective To evaluate the real‐world safety and efficacy for standard surgical risk patients with extracranial internal carotid artery disease undergoing transcarotid artery revascularization. Methods ROADSTER 3 is a prospective, multicenter, single‐arm post‐approval study.
Jeffrey Jim +15 more
wiley +1 more source
Case Reports in Medicine, 2013 A 69-year-old man was admitted to our hospital for persistent fever, myalgias, articular pain, headache, and hypoaesthesia of the scalp. The clinical scenario was typical for giant-cell arteritis.
Massimo Slavich +5 more
doaj +1 more source
Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants
Arthritis &Rheumatology, Volume 78, Issue 3, Page 734-742, March 2026.Objective Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2 ...
Jian Yue +55 more
wiley +1 more source
Antiphospholipid Immunoreactivity and TIAs
Pediatric Neurology Briefs, 1993 Clinical features that may predict the presence of antiphospholipid antibodies (aPL) in young patients with transient focal neurological events were determined in a study at the Henry Ford Hospital, Detroit, MI.
J Gordon Millichap
doaj +1 more source
Arthritis &Rheumatology, Volume 78, Issue 2, Page 385-393, February 2026.Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz +18 more
wiley +1 more source
Interdisciplinary Neurosurgery, 2021 Symptomatic cervical spinal stenosis and carotid artery stenosis are common neurosurgical diseases, but little is known about the management of their concurrent presentation.
Mark M. Zaki +3 more
doaj +1 more source
Clinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.ABSTRACT Objective The complement component 5 inhibitor therapies (C5ITs) eculizumab and ravulizumab are approved for the treatment of generalized myasthenia gravis (gMG). We evaluated the real‐world effectiveness and safety of eculizumab and ravulizumab in patients with gMG with or without prior intravenous immunoglobulin (IVIg) or plasma exchange ...
Akiyuki Uzawa +2 more
wiley +1 more source