Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
How to Foster Challenging Interdisciplinary Collaborations: Can Philosophy Support Neuroscientists? [PDF]
Kunze M +8 more
europepmc +1 more source
Programmable Elastic Wave Control Via Mechanical‐Acoustic Interaction in Bistable Metamaterials
A mechanically programmable metamaterial based on mechanical‐acoustic interaction enables reconfigurable elastic wave control through bistable state switching. Spatial encoding of peak and valley states tunes band structures and transmission, achieving low‐frequency vibration suppression, waveguiding, and energy localization.
Yuanyuan Li +7 more
wiley +1 more source
Ambiguities in Assigning Single-Crystal NMR Data to Individual Atoms in the Crystal Structure: A Case Study of Hambergite, Be<sub>2</sub>BO<sub>3</sub>OH, by <sup>9</sup>Be and <sup>11</sup>B NMR Spectroscopy, XRD Measurements and DFT Calculations. [PDF]
Steinadler J +6 more
europepmc +1 more source
Atomically dispersed CuOx (CPCu‐1) forms isolated Cu–Ov sites that enable defect‐mediated O2 activation and fast electron/proton transfer via interfacial synergy. In contrast, thick CuOx clusters (CPCu‐10) promote a surface‐adsorption‐controlled pathway with intermediate accumulation, highlighting a mechanism switch from interfacial activation to ...
Yang‐Yang Hsu +8 more
wiley +1 more source
AML with t(8;21): A Molecularly Defined Entity with Morphological Ambiguities [PDF]
Gajendra S, Gupta L, Sahoo R.
europepmc +1 more source
This work introduces state‐convergent polymerization (SCP), a polymerization framework in which chemically diverse reaction pathways converge toward a reproducible functional polymeric state rather than a defined molecular structure. Using melanin and polydopamine as exemplars, SCP explains how robust polymer functions emerge under chemical and ...
Seonki Hong
wiley +1 more source
Deciphering Morphological Variability: Addressing Taxonomic Ambiguities in Contemporary Species Delimitation (Hymenoptera, Figitidae). [PDF]
Ferrer-Suay M +3 more
europepmc +1 more source
Editorial: Exploring female intuition: insights into gendered information processing. [PDF]
Isenman L, Sinclair M.
europepmc +1 more source

