Results 31 to 40 of about 48,130 (264)

Ambiguities in helical reconstruction

open access: yeseLife, 2014
Helical polymers are found throughout biology and account for a substantial fraction of the protein in a cell. These filaments are very attractive for three-dimensional reconstruction from electron micrographs due to the fact that projections of these ...
Edward H Egelman
doaj   +1 more source

Sublogarithmic Ambiguity

open access: yesTheoretical Computer Science, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Ambiguity in Our Technical Society

open access: yesZygon, 2001
The spiritual situation at the turn of the millennium can be interpreted through Paul Tillich's appropriation of modernity, by analysis of the determinative structures and decisive trends of our age.
doaj   +2 more sources

Processing ambiguities in attachment and pronominal reference

open access: yesGlossa, 2020
The nature of ambiguity resolution has important implications for models of sentence processing in general. Studies of structural ambiguities, such as modifier attachment ambiguities, have generally supported a model in which a single analysis of ...
Brian Dillon   +2 more
doaj   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

"علم المبهمات – نشأته- أهميته -المؤلفات فيه " [PDF]

open access: yesMağallaẗ Kulliyyaẗ al-dirāsāt al-islāmiyyaẗ wa al-ʿarabiyyaẗ lil banat bi ğāmiʿaẗ Al-Ahzhar farʿ kafr Al-Sheikh
القرآن الكريم كتاب الله المجيد، لا يأتيه الباطل من بين يديه ولا مــــــن خلفـــــــه تنزيـــــــــــــلٌ من حكيمٍ حميد، أُحكِمت آياته، وحفظه الله من التغيير، وسلَّمه من التحريف والتبديل، أودع الله فيه خزائن المعارف، وكنوز العلم، وهو خير ما يَبذل فيه ...
محمود محمد عبدالمنعم حسن.
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Designer clown fishes: Unraveling the ambiguities

open access: yesFrontiers in Marine Science, 2022
The global marine ornamental fish trade is dominated by wild collected fishes, and the contribution from hatchery production is less than 10% of the total.
Kuttan Kuravamparambu Anikuttan   +19 more
doaj   +1 more source

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