Results 161 to 170 of about 1,228,351 (351)

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

LEARNING BY DOING IN AN AMBIGUOUS ENVIRONMENT [PDF]

We experimentally test whether risk aversion or ambiguity aversion can explain decisions in a learning by doing game. We first measure subjects' preferences toward risk and ambiguity, and then use these measures to predict behavior in the game.
Jim Engle-Warnick, Sonia Laszlo Author Email: sonia.laszlo@mcgill.ca   +1 more
core  

Ribosomal Ambiguity

Cold Spring Harbor Symposia on Quantitative Biology, 1966
L, Gorini, G A, Jacoby, L, Breckenridge
openaire   +2 more sources

Data‐Driven Printability Modeling of Hydrogels for Precise Direct Ink Writing Based on Rheological Properties

Advanced Science, EarlyView.
A predictive model for 3D printability is developed by integrating rheological analysis, including the Large Amplitude Oscillatory Shear (LAOS) test, with machine learning. With prediction errors under 10%, the model shows that post‐extrusion recovery controls horizontal printability, while high‐strain‐rate nozzle flow dictates vertical printability ...
Eun Hui Jeong, Jiho Choi, Han Bi Park, Ji Woo Lee, Seo Yeon Bae, Byoung Soo Kim, ChangKyu Yoon, Jun Dong Park   +7 more
wiley   +1 more source

Visual working memory affects the perception of ambiguous SFM (structure-from-motion) by enhance internally directed attention

, 2017
Jingjie Li, Hao Wu, Badong Chen
openalex   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

A.J. Cronin. A doctor into lifelong writer

Studia Humanitatis, 2013
Reality and fiction might be strictly coexistent in the narrative world. The author of this article, after a deep reading of A.J. Cronin’s novels, has tried to find out the right key to penetrate into the novelist’s intricate world.
Fusco Amedea
doaj  

Referee report. For: Alternative Types of Ambiguity and their Effects on Climate Change Regulation [version 1; peer review: 1 approved]

, 2022
John Beirne
openalex   +1 more source

Ambiguity in electoral competition. [PDF]

L'article propose une théorie de la compétition électorale ambigüe. Une plate-forme est ambigüe si les votants peuvent l'interpréter de différentes manières.
Jean-François Laslier
core