Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 [PDF]
Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional ...
De Preter, K +13 more
core +3 more sources
The 2024 Nobel prize in Medicine: impact on hemostasis and thrombosis research
On October 7th, the Nobel Prize in Physiology or Medicine was awarded jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation...
Loredana Bury +2 more
doaj +1 more source
In this third supplement to the Catalogue of Swiss spiders of Maurer & Hänggi (1990) 9 species are recorded for the first time for Switzerland. 4 additional species already published elsewhere are added to the list of Swiss spiders.
Hänggi, Ambros
doaj +1 more source
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23 [PDF]
Background: Recurrent loss of part of the long arm of chromosome 11 is a well established hallmark of a subtype of aggressive neuroblastomas. Despite intensive mapping efforts to localize the culprit 11q tumour suppressor gene, this search has been ...
Evi Michels +65 more
core +2 more sources
Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring [PDF]
Background miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during ...
Bruce, Kimberley D. +9 more
core +3 more sources
Access to arable land has the potential to address the challenges of poverty, unemployment and household food insecurity in South Africa. Despite these opportunities and limited income sources, particularly in former homelands of the country, smallholder
Felicity Aphiwe Mkhongi +2 more
doaj +1 more source
The global decline in biodiversity can be partly ameliorated by sympathetic design of green spaces within urban environments. This includes roundabouts on road systems. This study utilised a combination of approaches to assess levels of plant and bacterial diversity in roundabouts of varying size, soil characteristics and habitat complexity.
Ethan Mitchell‐Innes +4 more
wiley +1 more source
The \u3cem\u3elet-7\u3c/em\u3e MicroRNA Family Members \u3cem\u3emir\u3c/em\u3e-48, \u3cem\u3emir\u3c/em\u3e-84, and mir-241 Function Together to Regulate Developmental Timing in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]
The microRNA let-7 is a critical regulator of developmental timing events at the larval-to-adult transition in C. elegans. Recently, microRNAs with sequence similarity to let-7 have been identified.
Abbott, Allison L. +6 more
core +1 more source
A 6-gene signature identifies four molecular subgroups of neuroblastoma [PDF]
Background: There are currently three postulated genomic subtypes of the childhood tumour neuroblastoma (NB); Type 1, Type 2A, and Type 2B. The most aggressive forms of NB are characterized by amplification of the oncogene MYCN (MNA) and low expression ...
Frida Abel (3966878) +10 more
core +2 more sources
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo +7 more
wiley +1 more source

