Results 131 to 140 of about 682,662 (388)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Ambulatory thyroidectomy: an anesthesiologist’s perspective

open access: yesLocal and Regional Anesthesia, 2017
Benjamin Murray,1 Sankalap Tandon,2 Ged Dempsey1 1Department of Anaesthesia and Critical Care, 2Department of Otolaryngology, Head & Neck Surgery, Aintree University Hospital NHS Foundation Trust, Liverpool, UK Abstract: Thyroidectomy has been ...
Murray B, Tandon S, Dempsey G
doaj  

Center of mass movement estimation using an ambulatory measurement system [PDF]

open access: yes, 2008
Human body movement analysis is done in so-called 'gait-laboratories' where several gait variables are estimated by measurement systems such as optical position measurement systems, EMG or force plates.
Asseldonk, E.H.F. van   +3 more
core   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

A clinical case of post-COVID-19 myoendocarditis and arrhythmic syndrome at the outpatient stage [PDF]

open access: yesКлиническая практика
Background: Infection with the SARS-CoV-2 virus entails the development of complications which affect the prognosis of the underlying disease. More than 40% of COVID-19 complications represent diseases of the cardiovascular system, most of which are the ...
Tatiana S. Pavlyukova   +8 more
doaj   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics

open access: yesAdvanced Science, EarlyView.
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen   +8 more
wiley   +1 more source

Ambulatory blood pressure monitoring in pregnancy induced hypertension

open access: yesActa Obstetricia et Gynecologica Scandinavica, 1997
Objective. To determine the role of ambulatory blood pressure monitoring in the diagnosis of pregnancy‐induced hypertension in women detected as hypertensive in the clinic by the conventional method. Design.
Arijit Biswas   +3 more
doaj   +1 more source

Surface Engineered Biomolecular Condensates for Targeted Cell Cytotoxicity

open access: yesAdvanced Science, EarlyView.
Interfacial engineering of biomolecular condensates with a decanoic acid (DA) membrane enables molecular‐weight‐gated enzyme localization. Small biomolecules (≤60 kDa) enrich internally, while high‐molecular‐weight alkaline phosphatase (ALP) localizes at the interface.
Chengying Yin   +6 more
wiley   +1 more source

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