The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis +7 more
wiley +1 more source
Cohort profile: AMBulatoRy blOod preSsure in older adults (AMBROSIA) and AMBROSIA-HOME. [PDF]
Reynolds K +16 more
europepmc +1 more source
Abstract Aerobic exercise testing helps facilitate recovery post‐concussion. Current protocols (Calgary Concussion Cycling Test: CCCT) are inaccessible for athletes with lower‐body impairments (i.e. Para athletes). This study compared physiological parameters for a novel arm crank test, the Calgary Adapted aRm Ergometer (CARE) test, with the CCCT ...
Jonathan D. Smirl +12 more
wiley +1 more source
Ambulatory blood pressure monitoring, European guideline targets, and cardiovascular outcomes: an individual patient data meta-analysis. [PDF]
Zhang DY +27 more
europepmc +1 more source
Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Clinical Inertia in the Diagnosis and Management of Hypertension Following Ambulatory Blood Pressure Monitoring. [PDF]
Flatow JS +6 more
europepmc +1 more source
Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin +8 more
wiley +1 more source
Association of Longitudinal Change in Ambulatory Blood Pressure With Cognitive Decline in Older Adults. [PDF]
Hoshide S +3 more
europepmc +1 more source
Abstract Lower sedentary behaviour (SB) has been associated with reduced cardiovascular disease and mortality. Yet, few trials have evaluated cardiovascular mechanisms of benefit. We examined the effects of a SB reduction intervention on heart rate variability (HRV) and cardio‐metabolic biomarkers.
Abdullah Bandar Alansare +6 more
wiley +1 more source
Unmasking the Clock: Diurnal Blood Pressure Variation in Patients With Type 2 Diabetes Mellitus With Hypertension via Ambulatory Blood Pressure Monitoring (ABPM). [PDF]
Shankar S +5 more
europepmc +1 more source

