ABSTRACT Simvastatin, an HMG‐CoA reductase inhibitor, is widely used for hypercholesterolemia but may cause myotoxicity linked to its plasma concentration. Pharmacokinetic gene polymorphisms influence inter‐individual variability in simvastatin exposure.
Sayanit Tipnoppanon+10 more
wiley +1 more source
Underutilization of ambulatory blood pressure monitoring in locally and nationally representative samples of patients with childhood-onset systemic lupus erythematosus. [PDF]
Chang JC+4 more
europepmc +1 more source
Protein Biomarkers in Venous Leg Ulcer Fluid: A Systematic Review
ABSTRACT Venous leg ulcers (VLUs) are common and cause significant morbidity and poor quality of life. There is a poor understanding of the biology underlying non‐healing VLUs. VLU exudates may reflect the underlying wound microenvironment. This systematic review aims to identify potentially diagnostic and/or prognostic protein biomarkers within VLU ...
Renitha Reddi+3 more
wiley +1 more source
ABSTRACT Elevated blood pressure variability (BPV) is an emerging independent risk factor for increased cardiovascular diseases (CVD). Many studies are exploring the impacts of regular physical exercise on reducing BPV. This study aimed to investigate whether exercise can be an intervention to control for the short‐term and long‐term BPV.
Ziyu Hao+4 more
wiley +1 more source
Ambulatory blood pressure monitoring. Effects of physical activity [PDF]
Cavelaars, MN (Marinel)
core +2 more sources
The role of ambulatory blood pressure monitoring in enhancing medication adherence among patients with newly diagnosed hypertension: an analysis of the National Health Insurance cohort database. [PDF]
Kim HL+5 more
europepmc +1 more source
D‐ and L‐Amino Acid Blood Concentrations Are Affected in Children With Duchenne Muscular Dystrophy
ABSTRACT Duchenne muscular dystrophy (DMD) is an X‐linked disease caused by the absence of functional dystrophin in the muscle cells. Recent untargeted metabolomics studies identified amino acid metabolism alterations as biochemical pathways potentially involved in DMD pathogenesis.
Martina Garofalo+9 more
wiley +1 more source
Reclassification of Adolescent Ambulatory Prehypertension and Unclassified Blood Pressures by 2022 American Heart Association Pediatric Ambulatory Blood Pressure Monitoring Guidelines. [PDF]
Hill-Horowitz T+8 more
europepmc +1 more source
In SURPASS J‐mono, tirzepatide‐mediated non‐glycemic and glycemic parameter improvements appeared differentially associated with weight loss, suggesting both weight loss‐associated and ‐unassociated effects of tirzepatide. ABSTRACT Aims/Introduction In the SURPASS J‐mono trial, tirzepatide demonstrated significant improvements in bodyweight and several
Hanaka Mimura+5 more
wiley +1 more source
High versus low measurement frequency during 24-h ambulatory blood pressure monitoring - a randomized crossover study. [PDF]
Thomsen MB+4 more
europepmc +1 more source