Results 91 to 100 of about 328,577 (288)

USE OF ORAL CHEMOTHERAPEUTIC MEDICATIONS IN NON-TRADITIONAL AMBULATORY SETTINGS [PDF]

open access: yes, 2009
Background: Cancer is the second leading cause of death in economically developed countries. The use and availability of oral treatment for cancer has increased dramatically in the past 10 years. Few studies have described the use of oral chemotherapy in
Arora, Sameer
core   +2 more sources

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu   +17 more
wiley   +1 more source

Linking nursing workload and performance indicators in ambulatory care [PDF]

open access: yes, 2006
More and more ambulatory care organizations are using nursing report cards to monitor and evaluate the quality and effectiveness of nursing care in the ambulatory setting.
Griffin, Karen F., MSN, RN, CNAA   +1 more
core   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

open access: yesAdvanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu   +20 more
wiley   +1 more source

A prospective study assessing agreement and reliability of a geriatric evaluation

open access: yesBMC Geriatrics, 2017
Background The present study takes place within a geriatric program, aiming at improving the diagnosis and management of geriatric syndromes in primary care.
Isabella Locatelli   +4 more
doaj   +1 more source

Atrial fibrillation : a common arrhythmia with possible dire consequences [PDF]

open access: yes, 2010
The diagnosis of atrial fibrillation (AF) is clinched on the electrocardiogram with the finding of fine baseline oscillations, absent P waves and irregular ventricular rhythm.1 It is the most common type of arrhythmia requiring medical care, with a ...
Xuereb, Robert G.
core  

A Model for Measuring Ambulatory Access to Care Recovery after Disasters [PDF]

open access: yes, 2018
Introduction: Although little research has examined impacts of disasters on scheduled ambulatory care services, routine care delivery is important for emergency planning and response because missed or delayed care can lead to more urgent care needs ...
Chu, Karen   +3 more
core   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

open access: yesAdvanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao   +16 more
wiley   +1 more source

A Novel Transfer Learning‐Based Hybrid EEG‐fNIRS Brain‐Computer Interface for Intracerebral Hemorrhage Rehabilitation

open access: yesAdvanced Science, EarlyView.
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen   +18 more
wiley   +1 more source

Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis

open access: yesBMC Medicine, 2017
Background The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria through a systematic review and meta-analysis.
Paulina Sypniewska   +5 more
doaj   +1 more source

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