Results 131 to 140 of about 4,957,759 (352)

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang   +7 more
wiley   +1 more source

Disease-Management Programs Can Improve Quality of Care for the Chronically Ill, Even in a Weak Primary Care System: A Case Study From Germany [PDF]

open access: yes, 2011
Examines how Germany's disease management programs featuring information technology support, designated ambulatory care doctors, focus on self-management, quality assurance, and financial incentives raised quality and satisfaction.
Dagmar Starke   +3 more
core  

Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database study.

open access: yesLancet. Infectious Diseases (Print), 2021
Houyu Zhao   +6 more
semanticscholar   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis

open access: yesBMC Medicine, 2017
Background The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria through a systematic review and meta-analysis.
Paulina Sypniewska   +5 more
doaj   +1 more source

Developing a Business Case for the Care Coordination and Transition Management Model: Need, Metrics, and Measures [PDF]

open access: yes, 2019
In this descriptive qualitative study, nurse and healthcare leaders\u27 experiences, perceptions of care coordination and transition management (CCTM®), and insights as to how to foster adoption of the CCTM RN role in nursing education, practice across ...
Brown, PhD, RN, CPHQ, FNAHQ, FAAN, Diane Storer   +5 more
core   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Connecting the uninsured to care: Engaging new primary care patients at a new York City safety net system

open access: yesPreventive Medicine Reports
Objective: Cost and ineligibility are major barriers to accessing United States health care, particularly for undocumented immigrants. NYC Care is a healthcare benefit program covering care at NYC Health+Hospitals, the nation's largest safety net system ...
Caroline Cooke   +3 more
doaj   +1 more source

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