Results 41 to 50 of about 37,767 (259)

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Role of private sector in providing tuberculosis care: Evidence from a population-based survey in India

Journal of Global Infectious Diseases, 2011
Background: In India, a large segment of the population seeks health care services from individual or institutional private health-care providers for health care.
Indrajit Hazarika
doaj   +1 more source

Single‐Incision Laparoscopy‐First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective study of 289 patients with Crohn's disease undergoing a single‐incision laparoscopy‐first (SILS‐first) strategy, conversion to open surgery was required in only 11.8% of cases. Fistula formation, colon resection, and smoking history were identified as independent risk factors for conversion, while postoperative complications and ...
Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Hiroki Ikeuchi   +9 more
wiley   +1 more source

Care-seeking strategies of migrants during the transition from a specific primary healthcare facility for uncovered individuals to common ambulatory general practice: A French qualitative study

BMC Public Health
Background Migrants have complex health needs but face multiple barriers to accessing health care. In France, permanent healthcare access offices (PASSs), as specific primary health care facilities (SPHCs), provide care to people without health insurance
Jego Maeva, Desrues Anne, Fall Marie, Janczewski Aurélie, Gentile Gaetan, Auquier Pascal, Tabélé Clémence, Khouani Jérémy   +7 more
doaj   +1 more source

One‐Year Healthcare Utilization and Costs After Emergency Department Encounters for Uncomplicated Appendicitis: A Statewide Observational Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective Non‐operative management with antibiotics has emerged as an alternative to appendectomy for uncomplicated appendicitis. This study compared one‐year healthcare costs and utilization outcomes after operative versus non‐operative management of uncomplicated appendicitis using statewide administrative data.
Andrew C. Meltzer, Michael Makutonin, Taylor Gorak, Aditya Loganathan, Jack A. Meltzer, Avi Dor   +5 more
wiley   +1 more source

Femoroacetabular Impingement Morphological Changes in Sample of Patients Living in Southern Mexico Using Tomographic Angle Measures

Tomography
Background: Femoroacetabular impingement (FAI) is a condition caused by abnormal contact between the femur head and the acetabulum, which damages the labrum and articular cartilage.
Ricardo Cardenas-Dajdaj, Arianne Flores-Rivera, Marcos Rivero-Peraza, Nina Mendez-Dominguez   +3 more
doaj   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

AI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury, Kandarpa Kumar Sarma, Lachit Dutta   +2 more
wiley   +1 more source

Characteristics and management of patients attending primary asthma clinics in primary health care in the Kingdom of Bahrain: A cross-sectional study

Journal of Family Medicine and Primary Care
Introduction: Asthma remains poorly controlled worldwide despite clinical guidelines, continuing to cause high morbidity and mortality. This study examines the clinical characteristics, management practices, and factors affecting asthma control in ...
Fatema Ahmed Al Jerdabi, Mahmood Alawainati, Abeer AbdulRahman AlSaweer, Fadhel Abbas Arafat, Mohamed Alhalwaji, Eman Sayed Mahmood Sharaf, Lamees Al Aradi   +6 more
doaj   +1 more source

Restructuring the final year of the model study programme MaReCuM at the Medical Faculty Mannheim: the academic quarter in ambulatory medicine

GMS Journal for Medical Education, 2019
Introduction: To reflect the ever-growing importance of outpatient care in medical education, MaReCuM – a reformed curriculum, also referred to as a model study programme – was introduced at the Medical Faculty Mannheim in 2006. It divided the final year
Liebke, Lisa, Narciß, Elisabeth, Obertacke, U., Fritz-Joas, Harald   +3 more
doaj   +1 more source

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang, Yuan Fang, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula R. Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, Laura Hagerty, Yetrib Hathout, Michael Ziemba, Lauren Morgenroth, Surajit Bhattacharya, Kanneboyina Nagaraju, Jyoti K. Jaiswal, Eric P. Hoffman   +16 more
wiley   +1 more source