Results 81 to 90 of about 2,636,091 (255)

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Naturalistic monitoring of the affect-heart rate relationship: A Day Reconstruction Study [PDF]

open access: yes
Objective: Prospective studies have linked both negative affective states and trait neuroticism with hypertension, cardiovascular disease, and mortality.
Malcolm MacLachlan   +4 more
core  

Landelijke database Stichting hiv monitoring

open access: yes, 2023
Door de minister van VWS zijn in totaal 24 erkende hiv-behandelcentra of sub-centra aangewezen die samenwerken met Stichting hiv monitoring (SHM) om data te verzamelen van mensen  met hiv en in zorg zijn in een hiv-behandelcentrum in Nederland. Daarnaast
Stichting hiv monitoring (SHM)
core  

Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation

open access: yesAdvanced Science, EarlyView.
A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz   +3 more
wiley   +1 more source

The relationship between 24 hr. central ambulatory blood pressure and arterial stiffness

open access: yes, 2019
Access to thesis permanently restricted to Ball State community only.The relationship between blood pressure and arterial stiffness is complex and remains incompletely understood. This study aimed to examine the relationship between 24 hr.
Martin, Elizabeth J.
core  

Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus [PDF]

open access: yes, 2013
Systolic and diastolic blood pressures display a circadian rhythmicity that can be assessed by 24-hour ambulatory blood pressure monitoring and analysed using the cosinor procedure. Altered characteristics to the circadian rhythm of blood pressure, which
Elena Matteucci   +3 more
core  

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

State of Blood Pressure in Children with Juvenile Rheumatoid Arthritis

open access: yesZdorovʹe Rebenka, 2013
Children with juvenile rheumatoid arthritis (JRA) has increased risk for pathological changes of blood pressure (BP) due to development of endothelial dysfunction, increase in vascular wall stiffness and treatment with systemic glucocorticosteroids (GCS)
I.V. Romankevych
doaj   +1 more source

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