Results 91 to 100 of about 47,911 (266)

Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X‐Linked Dystonia Parkinsonism

open access: yesAnnals of Neurology, EarlyView.
Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Adelie Y.S. Tan   +19 more
wiley   +1 more source

Omnidirectional Circularly Polarized Monopole Antennas on Artificial Magnetic Conductor Ground Plane

open access: yesIEEE Access
This research proposes omnidirectional circularly polarized monopole antennas (OCPA) with single-annular (SA-AMC) and dual-annular artificial magnetic conductor (DA-AMC) ground planes.
Pisit Janpangngern   +3 more
doaj   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner   +28 more
wiley   +1 more source

Comprehensive Medial Knee Four‐Arm Reconstruction to Address Complex Instability With Hamstring Autograft

open access: yesArthroscopy Techniques, EarlyView.
Abstract Medial knee ligament injuries are increasingly recognized as complex, multiplanar lesions, resulting not only in simple medial instability but also anteromedial rotatory instability, anteromedial instability, posteromedial instability, posteromedial rotatory instability, and post‐traumatic medial asymmetric hyperextension.
Konrad Malinowski   +5 more
wiley   +1 more source

Two Hundred Eighty Characters of Environment: Relative Environmental Performance, Strategic Communication, and Firm Value

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Corporate environmental communication has become an essential aspect of modern business practices, as stakeholders increasingly demand transparency and accountability regarding sustainability efforts. Within this context, we examine whether firms use environmental communication on X/Twitter to offset weaker relative environmental performance ...
Ivan Russo   +3 more
wiley   +1 more source

Corporate Indigenous Stakeholder Engagement in the Sustainability Reporting: Evidence From the Australian Mining Industry

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Given the growing pressure for indigenous stakeholder engagement, this paper explores the extent and nature of indigenous stakeholder engagement disclosures in the sustainability reporting of Australian mining companies. Drawing on stakeholder theory and legitimacy theory, this study explores how large Australian mining companies disclose ...
Md. Moazzem Hossain   +5 more
wiley   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

open access: yesChemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma   +13 more
wiley   +1 more source

Oportuna advertencia a los Médicos.

open access: yesMedicina, 1999
<p><em><strong>La Junta Directiva de la Asociación Médica Colombiana consideró conveniente enviar a todos los </strong></em><em><strong>colegas del país la Circular que reproducimos y con cuyos términos está ...
Asociación Medica Colombiana AMC
doaj  

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