Results 11 to 20 of about 14,096,383 (244)
Symptomatologie, epidemiologie des fusarioses sur cereales
*INRA, Amelioration des Plantes, BP29, 35650 Le Rheu, FRA Diffusion du document : INRA, Amelioration des Plantes, BP29, 35650 Le Rheu, FRAInternational ...
Maurin, Nicolas +2 more
core +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
*INRA, Station de Genetique et Amelioration des Plantes, Route de Saint Cyr, 78026 Versailles Cedex Diffusion du document : INRA, Station de Genetique et Amelioration des Plantes, Route de Saint Cyr, 78026 Versailles Cedex Diplôme : Dr.
Pham, J.L.
core +2 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan +8 more
wiley +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
*INRA, Station de Genetique et Amelioration des Plantes, Route de Saint Cyr, 78026 Versailles Cedex Diffusion du document : INRA, Station de Genetique et Amelioration des Plantes, Route de Saint Cyr, 78026 Versailles Cedex Diplôme : Dr.
Senghor, P.T.
core +2 more sources
La production des plantes haploïdes et haploïdes doublés, fournit aux sélectionneurs du blé un moyen très efficace pour accélérer la production des lignées homozygotes.
Fatima HENKRAR +3 more
doaj
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan +14 more
wiley +1 more source

