Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms
Cell Proliferation, Volume 59, Issue 1, January 2026.Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng +4 more
wiley +1 more source
4-phenylbutyrate Mitigates Fluoride-Induced Cytotoxicity in ALC Cells
Frontiers in Physiology, 2017 Chronic fluoride over-exposure during pre-eruptive enamel development can cause dental fluorosis. Severe dental fluorosis is characterized by porous, soft enamel that is vulnerable to erosion and decay.
Maiko Suzuki +3 more
doaj +1 more source
Histopathological Spectrum of a Calcifying Odontogenic Cyst With Uncommon Findings
Case Reports in Dentistry, Volume 2026, Issue 1, 2026.Calcifying odontogenic cyst (COC) is an uncommon lesion accounting for less than 1% of all odontogenic cysts. This pathology commonly affects the anterior jaw and is prevalent in the second to third decades of life, with no sex predilection. The lesion presents with a variable clinical and radiographic presentation, which can simulate other common jaw ...
Saraswoti Khadka +7 more
wiley +1 more source
The Importance of Connexin 43 in Enamel Development and Mineralization
Frontiers in Physiology, 2018 During enamel development, formation of hydroxyapatite crystals and regulation of pH in the enamel matrix require massive transport of ions. Both ameloblasts and adjacent dental epithelial cells in the stellate reticulum co-express several transmembrane ...
Sali Al-Ansari +12 more
doaj +1 more source
Primordial odontogenic tumor : an immunohistochemical profile [PDF]
, 2017 Primordial Odontogenic Tumor (POT) is a recently described odontogenic tumor characterized by a variably cellular loose fibrous tissue with areas similar to the dental papilla, covered by cuboidal to columnar epithelium that resembles the internal ...
Bologna Molina, Ronell +5 more
core +1 more source
G protein–coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts [PDF]
, 2020 Yuta Chiba +16 more
openalex +1 more source
Relationships between protein and mineral during enamel development in normal and genetically altered mice [PDF]
, 2011 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90093/1/EOS_871_sm_SupportingInformation.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/90093/2/j.1600-0722.2011.00871.x ...
Bartlett, John D. +5 more
core +1 more source
Expression of steroid receptors in ameloblasts during amelogenesis in rat incisors
Frontiers in Physiology, 2016 Endocrine disrupting chemicals (EDCs) play a part in the modern burst of diseases and interfere with the steroid hormone axis. Bisphenol A (BPA), one of the most active and widely used EDCs, affects ameloblast functions, leading to an enamel ...
Sophia Houari +10 more
doaj +1 more source
Les phosphoprotéines sécrétées liant le calcium (SCPP) impliquées dans la formation de l'émail dentaire : expression chez le lézard Anolis carolinensis et évolution chez les amniotes [PDF]
, 2015 Enamel formation requires the involvement of secretory calcium-binding phosphoproteins. Three of them, amelogenin (AMEL), ameloblastin (AMBN) and enamelin (ENAM), have been extensively studied in mammals.
Gasse, Barbara
core +2 more sources