Frontiers in Physiology, 2014 The hardest tooth enamel tissue develops from a soft layer of protein-rich matrix, predominated by amelogenin that is secreted by epithelial ameloblasts in the secretory stage of tooth enamel development.
Li eZhu +5 more
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Effect of phosphate group on remineralization of early enamel caries regulated by amelogenin peptide. [PDF]
PLoS ONEObjectiveTo show the effect of the phosphate group on the remineralization process of early enamel caries mediated by amelogenin peptide.MethodsFreshly extracted, completed, and crack-free bovine teeth were used to create artificial early enamel caries ...
Hualei Zhao, Qun Zhang, Jinpu Chu
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Lats1/2 Differentially Modulate the Proliferative State of Dental Epithelial Progenitors and Ameloblasts in the Murine Incisor. [PDF]
Orthod Craniofac ResABSTRACT Objective(s) YesâAssociated Protein (YAP) is a critical regulator of cell proliferation and differentiation, having the capacity to convert differentiated cells into somatic stem cells in several contexts. Here we investigate the plasticity of adult mouse dental epithelial cells by testing the effects of ectopic YAP activation in dental ...
Zhang Z +4 more
europepmc +2 more sources
Amelogenin Null Mice Develop Osteoarthritis, While Its Application Mitigates Disease Phenotypes in a Rat Model. [PDF]
FASEB JHelwa-Shalom O +12 more
europepmc +2 more sources
The Leucine-Rich Amelogenin Peptide Alters the Amelogenin Null Enamel Phenotype [PDF]
Cells Tissues Organs, 2020 <i>Introduction:</i> The amelogenin proteins secreted by ameloblasts during dental enamel development are required for normal enamel structure. <i>Amelx</i> null (KO) mice have hypoplastic, disorganized enamel similar to that of human patients with mutations in the <i>AMELX</i> gene, and provide a model system for ...
Carolyn W. Gibson +9 more
openalex +3 more sources
Explaining gender differences in caries: a multifactorial approach to a multifactorial disease. [PDF]
, 2010 Many studies have demonstrated that caries rates are higher in women than in men. This review attempts to provide an explanation for this trend by examining each factor which contributes to caries and how the factor differs in men and women. Evidence has
Ferraro, Maria, Vieira, Alexandre R
core +5 more sources
Molecular Exploration of the First-Century Tomb of the Shroud in Akeldama, Jerusalem [PDF]
, 2009 The Tomb of the Shroud is a first-century C. E. tomb discovered in Akeldama, Jerusalem, Israel that had been illegally entered and looted. The investigation of this tomb by an interdisciplinary team of researchers began in 2000.
Donoghue, HD +8 more
core +17 more sources
Identification of a novel splicing form of amelogenin gene in a reptile, Ctenosaura similis. [PDF]
PLoS ONE, 2012 Amelogenin, the major enamel matrix protein in tooth development, has been demonstrated to play a significant role in tooth enamel formation. Previous studies have identified the alternative splicing of amelogenin in many mammalian vertebrates as one ...
Xinping Wang, Xuliang Deng, Xichen Zhang
doaj +1 more source
Alternative Splicing of the Amelogenin Gene in a Caudate Amphibian, Plethodon cinereus. [PDF]
PLoS ONE, 2013 As the major enamel matrix protein contributing to tooth development, amelogenin has been demonstrated to play a crucial role in tooth enamel formation.
Xinping Wang +4 more
doaj +1 more source
One-step purification of recombinant human amelogenin and use of amelogenin as a fusion partner. [PDF]
PLoS ONE, 2012 Amelogenin is an extracellular protein first identified as a matrix component important for formation of dental enamel during tooth development. Lately, amelogenin has also been found to have positive effects on clinical important areas, such as ...
Johan Svensson Bonde, Leif Bulow
doaj +1 more source