Results 191 to 200 of about 5,706 (208)
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Biochemical and Biophysical Research Communications, 1992
A heterogeneous population of amelogenin proteins is derived from a single copy of the mouse amelogenin gene. To investigate the one gene--multiple protein enigma, we designed a study to distinguish between alternative splicing and proteolytic cleavage models.
Malcolm L. Snead+9 more
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A heterogeneous population of amelogenin proteins is derived from a single copy of the mouse amelogenin gene. To investigate the one gene--multiple protein enigma, we designed a study to distinguish between alternative splicing and proteolytic cleavage models.
Malcolm L. Snead+9 more
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Regulation of Amelogenin Gene Expression
Critical Reviews in Eukaryotic Gene Expression, 1999The X-chromosomal amelogenin gene is expressed at a high level by ameloblast cells within the enamel organ for a short time during tooth development. Therefore, expression is both tooth specific and developmentally regulated. A Y-chromosomal amelogenin gene is also active in human and cow, but has not been detected in mouse.
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Molecular Cloning of Bovine Amelogenin cDna
Advances in Dental Research, 1987Molecular cloning of a bovine amelogenin cDNA was accomplished by construction of a cDNA expression library (λgt11 cDNA library) from the bovine ameloblast mRNA and then screening of the library with antibodies to bovine amelogenins. The complete primary structure of an amelogenin was deduced from cloned cDNA.
M F Young+6 more
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Biopolymers, 1998
At the secretory stage of tooth enamel formation the majority of the organic matrix is composed of amelogenin proteins that are believed to provide the scaffolding for the initial carbonated hydroxyapatite crystals to grow. The primary objective of this study was to investigate the interaction between amelogenins and growing apatite crystals.
Alan G. Fincham+2 more
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At the secretory stage of tooth enamel formation the majority of the organic matrix is composed of amelogenin proteins that are believed to provide the scaffolding for the initial carbonated hydroxyapatite crystals to grow. The primary objective of this study was to investigate the interaction between amelogenins and growing apatite crystals.
Alan G. Fincham+2 more
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An Amelogenin Minigene to Study Alternative Splicing
DNA and Cell Biology, 2006Diversity in gene expression is commonly observed as a result of alternative splicing of RNA transcripts. This is true in the case of amelogenin, one of the enamel matrix proteins. Our hypothesis is that additional amelogenin mRNA transcripts are generated in vivo, but these transcripts have yet to be observed because of the limitations of currently ...
Jason L. Shapiro+4 more
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A Review of the Aggregation Properties of a Recombinant Amelogenin
Connective Tissue Research, 1995The present paper reviews some recent data on the aggregation properties of a recombinant amelogenin using dynamic light scattering, transmission electron microscopy, atomic force microscopy, and size exclusion chromatography. It was found that the recombinant amelogenin M179 molecules in solution form spherical monodisperse aggregates (15-20 nm) which
Janet Moradian-Oldak+5 more
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Amelogenin Gene Expression in Porcine Odontoblasts
Journal of Dental Research, 2002Amelogenin is the major organic component in the enamel matrix of developing teeth and plays an important role in enamel biomineralization. Amelogenin has been reported to be a specific secretory product of ameloblasts. In this study, we examined amelogenin gene expression in various cell layers prepared from a porcine permanent tooth germ using ...
Yasuo Yamakoshi+5 more
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Overview: A New Function of Amelogenin
Journal of Oral Biosciences, 2011Abstract Periodontal disease is a major concern in dentistry because it causes the loss of periodontal tissue, resulting in tooth loss that induces both aesthetic and functional problems for patients. Various methods have been used to facilitate the regeneration of lost or diseased periodontal tissue.
Masaki J. Honda, Naoto Suda
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Phylogenetic Distribution of Amelogenin Proteins and Amelogenin Genes in Vertebrates [PDF]
Masato Mikami+4 more
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Rare failures in the amelogenin sex test
International Journal of Legal Medicine, 2002Determination of sex using the amelogenin sex test is well established in the forensic field especially for casework and DNA databasing purposes. The sex test is part of commercially available PCR kits. Among 29,432 phenotypic male individuals stored in the Austrian National DNA database, 6 individuals were found to lack the amelogenin Y-specific PCR ...
Harald Niederstätter+3 more
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