Meeting report: a hard look at the state of enamel research. [PDF]
, 2017 The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D +13 more
core +1 more source
Amelogenin supramolecular assembly in nanospheres defined by a complex helix-coil-PPII helix 3D-structure. [PDF]
PLoS ONE, 2011 Tooth enamel, the hardest material in the human body, is formed within a self-assembled matrix consisting mostly of amelogenin proteins. Here we have determined the complete mouse amelogenin structure under physiological conditions and defined ...
Xu Zhang +3 more
doaj +1 more source
Use of human amelogenin in molecular encapsulation for the design of pH responsive microparticles
BMC Biotechnology, 2012 Background Proteins can be used in drug delivery systems to improve pharmacological properties of an active substance. Differences in pH between tissues can be utilized in order to achieve a targeted drug release at a specific location or tissue, such as
Bonde Johan, Bülow Leif
doaj +1 more source
Weaker dental enamel explains dental decay. [PDF]
PLoS ONE, 2015 Dental caries continues to be the most prevalent bacteria-mediated non-contagious disease of humankind. Dental professionals assert the disease can be explained by poor oral hygiene and a diet rich in sugars but this does not account for caries free ...
Alexandre R Vieira +4 more
doaj +1 more source
Establishment and characterization of two human breast carcinoma cell lines by spontaneous immortalization: Discordance between Estrogen, Progesterone and HER2/neu receptors of breast carcinoma tissues with derived cell lines [PDF]
, 2012 Background: Breast cancer is one of the most common cancers among women throughout the world. Therefore, established cell lines are widely used as in vitro experimental models in cancer research.Methods: Two continuous human breast cell lines, designated
Akmal, S.N. +6 more
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Regenerative potential of biphasic calcium phosphate and enamel matrix derivatives in the treatment of isolated interproximal intrabony defects: a randomized controlled trial [PDF]
Journal of Yeungnam Medical Science, 2022 Background The combined use of biomaterials for regeneration may have great biological relevance. This study aimed to compare the regenerative potential of biphasic calcium phosphate (BCP) alone and with growth factor enamel matrix derivatives (EMDs) for
Pritish Chandra Pal +5 more
doaj +1 more source
Molar incisor hypomineralisation: current knowledge and practice
International Dental Journal, EarlyView., 2020 Background Molar incisor hypomineralisation (MIH) is a common developmental dental condition that presents in childhood. Areas of poorly formed enamel affect one or more first permanent molars and can cause opacities on the anterior teeth. MIH presents a variety of challenges for the dental team as well as functional and social impacts for affected ...
Helen D. Rodd +4 more
wiley +1 more source
Comparison of Lagostomus maximus amelogenin gene (AMELX) with other mammals [PDF]
, 2016 The aim of this study was to compare the Lagostomus maximus AMEL sequence to assess their similarity with the AMEL genes from other mammals. Previously we reported a sequence of the AMEL gene of Lagostomus maximus which corresponds to the intron 3 of the
Espinosa, Maria Beatriz
core +1 more source
Mimicking amelogenesis to remineralize enamel through co-assembly of PTL fibrils and CMC/ACP
Materials & Design, 2023 Enamel remineralization has important clinical value for the prevention and minimally invasive treatment of early enamel caries. Enamel matrix proteins (EMPs) are believed to play a key role in amelogenesis to regulate the growth and organization of ...
Yangyang Ye +7 more
doaj +1 more source
The Exon 6ABC Region of Amelogenin mRNA Contribute to Increased Levels of Amelogenin mRNA through Amelogenin Protein-enhanced mRNA Stabilization [PDF]
Journal of Biological Chemistry, 2006 We recently demonstrated that the reuptake of full-length amelogenin protein results in increased levels of amelogenin mRNA through enhanced mRNA stabilization (Xu, L., Harada, H., Tamaki, T. Y., Matsumoto, S., Tanaka, J., and Taniguchi, A. (2006) J. Biol. Chem. 281, 2257-2262).
Liming, Xu +2 more
openaire +2 more sources