Results 41 to 50 of about 5,635 (209)

Changes in the C-terminal, N-terminal, and histidine regions of amelogenin reveal the role of oligomer quaternary structure on adsorption and hydroxyapatite mineralization

Frontiers in Physiology, 2022
Adsorption interactions between amelogenin and calcium phosphate minerals are believed to be important to amelogenin’s function in enamel formation, however, the role of specific amino acid residues and domains within the protein in controlling ...
Jinhui Tao, Emma Hanson, Alice C. Dohnalkova, Garry W. Buchko, Garry W. Buchko, Biao Jin, Wendy J. Shaw, Barbara J. Tarasevich   +7 more
doaj   +1 more source

The Exon 6ABC Region of Amelogenin mRNA Contribute to Increased Levels of Amelogenin mRNA through Amelogenin Protein-enhanced mRNA Stabilization [PDF]

Journal of Biological Chemistry, 2006
We recently demonstrated that the reuptake of full-length amelogenin protein results in increased levels of amelogenin mRNA through enhanced mRNA stabilization (Xu, L., Harada, H., Tamaki, T. Y., Matsumoto, S., Tanaka, J., and Taniguchi, A. (2006) J. Biol. Chem. 281, 2257-2262).
Akiyoshi Taniguchi, Liming Xu, Hidemitsu Harada   +2 more
openaire   +3 more sources

Analysis of the cells isolated from epithelial cell rests of Malassez through single-cell limiting dilution

Scientific Reports, 2022
The epithelial cell rests of Malassez (ERM) are essential in preventing ankylosis between the alveolar bone and the tooth (dentoalveolar ankylosis).
Syed Taufiqul Islam, Yoshihito Kurashige, Erika Minowa, Koki Yoshida, Durga Paudel, Osamu Uehara, Yunosuke Okada, Dembereldorj Bolortsetseg, Sayaka Sakakibara, Yoshihiro Abiko, Masato Saitoh   +10 more
doaj   +1 more source

Calcium interactions in amelogenin-derived peptide assembly

Frontiers in Physiology, 2022
Phosphorylation of serine residues has been recognized as a pivotal event in the evolution of mineralized tissues in many biological systems. During enamel development, the extracellular matrix protein amelogenin is most abundant and appears to be ...
Jing Zhang, Jing Zhang, Jing Zhang, Yushi Bai, Jian Wang, Bing Li, Stefan Habelitz, Jun-xia Lu   +7 more
doaj   +1 more source

Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions

The Anatomical Record, EarlyView.
Abstract This article reviews the pathological changes in the enamel of permanent mandibular cheek teeth and their sequelae in European roe deer from regions polluted by anthropogenic fluoride emissions. The primary (developmental) changes of fluorotic roe deer enamel are hypomineralization and microstructural aberrations, including enamel hypoplasia ...
Uwe Kierdorf, Horst Kierdorf
wiley   +1 more source

Synergistic Roles of Amelogenin and Ameloblastin

Journal of Dental Research, 2009
Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X −/− /Ambn −/− mice. These mice showed additional enamel defects in comparison with Amel X −/− or Ambn −/− mice.
Lillian Shum, Yoshihiko Yamada, Shigeki Suzuki, Junko Hatakeyama, Yuji Hatakeyama, Naoto Haruyama, Satoshi Fukumoto, Ashok B. Kulkarni, Takashi Nakamura, Carolyn W. Gibson   +9 more
openaire   +4 more sources

Amelogenin Exon 5 Peptide Promotes Cell Proliferation and Osteogenic Differentiation in Human Dental Pulp Stem Cells

Applied Sciences, 2019
Amelogenin is a complex enamel matrix protein that consists of various molecular-size proteins and amino acids. A spliced form of amelogenin was identified that included exons 2, 3, 5, 6, and 7.
Hirohito Kato, Yoichiro Taguchi, Isao Yamawaki, Yaru Ruan, Qingchao Wu, Yuji Nakano, Norimasa Tsumori, Takaya Nakata, Masahiro Noguchi, Makoto Umeda   +9 more
doaj   +1 more source

Restoration of human tooth enamel

BMEMat, EarlyView.
Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu, Bo Li, Mingrui Gao, Yangbei Li, Xiuyi Yang, Fengshi Li, Zhi Cai, Yi Liu, Shaojia Liu, Hewei Zhao, Lin Guo   +10 more
wiley   +1 more source

Role of the N-terminal peptide of amelogenin on osteoblastic differentiation of human mesenchymal stem cells [PDF]

European Cells & Materials, 2014
Porcine enamel matrix derivative (pEMD), a complex mixture of proteins and peptides including full-length amelogenin protein, splice variants, and proteolytic peptides, is used clinically with a carrier to regenerate supportive tissue around teeth ...
R Olivares-Navarrete, K Vesper, SL Hyzy, A Almaguer-Flores, BD Boyan, Z Schwartz   +5 more
doaj  

Preparative SDS PAGE as an Alternative to His-Tag Purification of Recombinant Amelogenin

Frontiers in Physiology, 2017
Recombinant protein technology provides an invaluable source of proteins for use in structure-function studies, as immunogens, and in the development of therapeutics.
Claire M. Gabe, Steven J. Brookes, Jennifer Kirkham   +2 more
doaj   +1 more source