Calcium interactions in amelogenin-derived peptide assembly
Frontiers in Physiology, 2022 Phosphorylation of serine residues has been recognized as a pivotal event in the evolution of mineralized tissues in many biological systems. During enamel development, the extracellular matrix protein amelogenin is most abundant and appears to be ...
Jing Zhang +7 more
doaj +1 more source
Silicon µPCR chip for forensic STR profiling with hybeacon probe melting curves [PDF]
, 2019 The demand to perform forensic DNA profiling outside of centralized laboratories and on the crime scene is increasing. Several criminal investigations would benefit tremendously from having DNA based information available in the first hours rather than ...
Cornelis, Senne +8 more
core +2 more sources
Posttranslational Amelogenin Processing and Changes in Matrix Assembly during Enamel Development
Frontiers in Physiology, 2017 The extracellular tooth enamel matrix is a unique, protein-rich environment that provides the structural basis for the growth of long and parallel oriented enamel crystals.
Mirali Pandya +10 more
doaj +1 more source
STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]
, 2017 The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne +5 more
core +2 more sources
Enamel proteins and proteases in Mmp20 and Klk4 null and double‐null mice [PDF]
, 2011 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90347/1/j.1600-0722.2011.00866.x ...
Bartlett +55 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Subfractions of enamel matrix derivative differentially influence cytokine secretion from human oral fibroblasts. [PDF]
, 2015 Enamel matrix derivative is used to promote periodontal regeneration during the corrective phase of the treatment of periodontal defects. Our main goal was to analyze the bioactivity of different molecular weight fractions of enamel matrix derivative ...
Brookes, SJ +5 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Immunohistochemical Study of Amelogenin Binding Proteins in an Amelogenin Point Mutation Mouse [PDF]
International Journal of Morphology, 2019 SUMMARY: Amelogenin is one of the enamel matrices secreted by ameloblasts. A mutation of the amelogenin gene can cause hereditary dental enamel defects known as amelogenesis imperfecta (AI). Since lysosome-associated membrane protein-1 (LAMP-1), -3 (LAMP-3), and 78kDa glucose-related protein (Grp78) were identified as binding proteins of amelogenin ...
Otawa-Kamogashira, Naoko +5 more
openaire +2 more sources
Role of the N-terminal peptide of amelogenin on osteoblastic differentiation of human mesenchymal stem cells [PDF]
European Cells & Materials, 2014 Porcine enamel matrix derivative (pEMD), a complex mixture of proteins and peptides including full-length amelogenin protein, splice variants, and proteolytic peptides, is used clinically with a carrier to regenerate supportive tissue around teeth ...
R Olivares-Navarrete +5 more
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