Results 61 to 70 of about 5,635 (209)

Comparative calcium binding of leucine‐rich amelogenin peptide and full‐length amelogenin

European Journal of Oral Sciences, 2006
Leucine‐rich amelogenin peptide (LRAP) is an alternately spliced amelogenin. LRAP is known to bind to hydroxyapatite, and has been shown to signal mesenchymal cells to proliferate, but its function in enamel formation is unclear. The purpose of this study was to determine the calcium‐binding properties and structure of recombinant human LRAP (rLRAP ...
Le, Thuan Q, Gochin, Miriam, Featherstone, John DB, Li, Wu, DenBesten, Pamela K   +4 more
openaire   +5 more sources

Mimicking amelogenesis to remineralize enamel through co-assembly of PTL fibrils and CMC/ACP

Materials & Design, 2023
Enamel remineralization has important clinical value for the prevention and minimally invasive treatment of early enamel caries. Enamel matrix proteins (EMPs) are believed to play a key role in amelogenesis to regulate the growth and organization of ...
Yangyang Ye, Runqiu Lu, Hao Ren, Yang Yang, Tianqi Li, Xiangyu Zhang, Peng Yang, Xu Zhang   +7 more
doaj  

Tracking Endogenous Amelogenin and Ameloblastin In Vivo

PLoS ONE, 2014
Research on enamel matrix proteins (EMPs) is centered on understanding their role in enamel biomineralization and their bioactivity for tissue engineering. While therapeutic application of EMPs has been widely documented, their expression and biological function in non-enamel tissues is unclear.
Jacques, J., Hotton, D., De la Dure-Molla, M., Petit, S., Asselin, A., Kulkarni, AB., Gibson, CW., Brookes, SJ., Berdal, A., Isaac, J.   +9 more
openaire   +7 more sources

A BiO‐Optimizing Site Targeted (BOOST) Approach to Periodontal Regeneration Through Local Doxycycline Prior to Surgery: A Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
Localized pre‐surgical modulation of inflammation using doxycycline (BOOST) improved early wound healing and enhanced clinical and radiographic outcomes of periodontal regeneration at 1 year, demonstrating significant benefits in terms of CAL gain, defect fill, and pocket closure compared to standard care.
Mario Aimetti, Giacomo Baima, Virginia Lorenzetti, Nargiz Aliyeva, Mario Bottone, Giulia Maria Mariani, Federica Romano   +6 more
wiley   +1 more source

The nucleation and growth of calcium phosphate by amelogenin [PDF]

Journal of Crystal Growth, 2007
The nucleation processes involved in calcium phosphate formation in tooth enamel are not well understood but are believed to involve proteins in the extracellular matrix. The ability of one enamel protein, amelogenin, to promote the nucleation and growth of calcium phosphate was studied in an in vitro system involving metastable supersaturated ...
Jenna L. Larson, Wendy J. Shaw, Barbara J. Tarasevich, James P. Simmer, Michael L. Paine, Malcolm L. Snead, Christopher J. Howard   +6 more
openaire   +3 more sources

Amelogenin as a regenerative endodontic molecule for immature teeth with apical periodontitis. An experimental study

Journal of Oral Biology and Craniofacial Research, 2022
Vitality of the dentin-pulp complex depends on cell activity and signalling processes. Amelogenin protein regulates cell signalling pathways during tooth development by activating the Wnt/β-catenin intercellular signalling pathway.
Maha M.F. Mounir, Fatma M. Rashed, Sahar M. Bukhary   +2 more
doaj  

Phosphorylated and Non-phosphorylated Leucine Rich Amelogenin Peptide Differentially Affect Ameloblast Mineralization

Frontiers in Physiology, 2018
The Leucine Rich Amelogenin Peptide (LRAP) is a product of alternative splicing of the amelogenin gene. As full length amelogenin, LRAP has been shown, in precipitation experiments, to regulate hydroxyapatite (HAP) crystal formation depending on its ...
Elvire Le Norcy, Elvire Le Norcy, Julie Lesieur, Jeremy Sadoine, Gaël Y. Rochefort, Catherine Chaussain, Catherine Chaussain, Anne Poliard   +7 more
doaj   +1 more source

A Generalized Approach to Genetic Sex Detection of Uniparous Mammalian Species, With High Potential in Foetal Sex Determination Using Circulating Cell‐Free DNA of Maternal Plasma

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Foetal sex determination of uniparous mammals with long gestation benefits the management of economically important domestic animals as well as captive wild populations, but the various methods currently available are limited to a few species. Based on the hypothesized presence of circulating cell‐ free foetal DNA (ccff‐DNA) in the maternal circulation
Hanna Kőszegi, Orsolya Zorkóczy, Alexandra Biácsi, Endre Sós, András Gáspárdy, Petra Zenke   +5 more
wiley   +1 more source

Wolf Population Size and Composition in One of Europe's Strongholds, the Romanian Carpathians

Ecology and Evolution, Volume 15, Issue 4, April 2025.
Noninvasive DNA monitoring of wolf packs in the Romanian Carpathians revealed pack composition changes from 1 year to another. Using a spatially explicit capture–recapture framework, we estimated population density at 2.35 wolves/100 km2. Our results suggest that monitoring wolf population size and composition is feasible in the Romanian Carpathians ...
Ruben Iosif, Tomaž Skrbinšek, Nándor Erős, Marjeta Konec, Barbara Boljte, Maja Jan, Barbara Promberger‐Fürpass   +6 more
wiley   +1 more source

Amelogenin: a Protein to Smile About

PLoS Biology, 2009
​HowHow did we humans (and other vertebrates) get our sparkling smiles? The hard white coating on our teeth, the enamel, is made up of hydroxyapatite—the same mineral that forms our bones. In our teeth, hydroxyapatite is organized into parallel arrays of columnar apatite crystals called prisms. The growth and organization of enamel prisms is controlled
openaire   +5 more sources