Results 231 to 240 of about 467,085 (284)

Delineating Structural Functionalities of Lenacapavir Amenable to Modifications for Targeting Emerging Drug-Resistant HIV‑1 Capsid Variants. [PDF]

ACS Med Chem Lett
Adu-Ampratwum D, Annamalai AS, Dinh T, Lockwood JR, Bockbrader RH, Haney R, Kvaratskhelia M, Fuchs JR.   +7 more
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Management of walled-off pancreatic necrosis (WON) beyond the conventional step-up strategy: a retrospective cohort study. [PDF]

Surg Endosc
Ebrahim M, Lauritsen ML, Schefte DF, Olsen GA, Novovic S, Karstensen JG.   +5 more
europepmc   +1 more source

Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces

Advanced Science, EarlyView.
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein, Renan Colucci, Xin Wei, Tsvetomir Ivanov, Katharina Landfester, Ulrike Kraft, Maria Villiou   +6 more
wiley   +1 more source

<i>C. elegans</i> as a tractable infection model for the emerging fungal pathogen <i>Candida auris</i>. [PDF]

Microbiol Spectr
Martinez M, Cruz MR, Garsin DA, Lorenz MC.   +3 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

SALVOVAR: a pragmatic randomized phase III trial comparing the SALVage weekly dose-dense regimen to the standard 3-weekly regimen in patients with poor prognostic OVARian cancers. [PDF]

Ther Adv Med Oncol
Chator C, Yanaihara N, Chabaud S, Parma GM, Dima AL, Clamp A, Ferron G, Kroep JR, Leary A, Cibula D, Fiteni F, Bruchim I, Serrier H, Carroll S, Belmont AS, Peron J, You B.   +16 more
europepmc   +1 more source

Electrophotochemical Decarboxylative C-H Fluoroalkylation via a Fe₂O₃-FTO Active Photoanode. [PDF]

ACS Catal
Motornov V, Liu Z, Imaoka K, Trienes S, Kang H, Weitz RT, Ackermann L.   +6 more
europepmc   +1 more source

Circulating tumor DNA accelerates diagnosis and treatment guidance for metastatic uveal melanoma with hepatic lesions not amenable to biopsy. [PDF]

Melanoma Res
Kissinger CR, Miller DJ, Li Z, Ashraf UM, Hubbard G, Wilson MA.   +5 more
europepmc   +1 more source

What counts as a core intervention component? Developing the Core-FAST (Fidelity and Adaptation for Scaling up Tool) plug-in. [PDF]

Implement Sci Commun
Best S, Price E, Cherednichenko B, Underhill C, Hilmy I, Fehlberg Z, Taylor N.   +6 more
europepmc   +1 more source