Results 31 to 40 of about 985,439 (307)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Have the relaxations in legislation related to termination of pregnancy made abortions safe in India? A meta-analysis on the prevalence of unsafe abortions among 15–49-year-old females in India

open access: yesCHRISMED Journal of Health and Research, 2022
Background: Pregnancy which is not terminated within the boundaries of legal definition in India is called an unsafe abortion. Objective: To observe the proportion of unsafe abortions among total abortions in 15–49-year-old ever married women across ...
Sneha Kumari   +7 more
doaj   +1 more source

Applying the Private Benefit Doctrine to Farmland Conservation Easements [PDF]

open access: yes, 2013
Farmland or working-land conservation easements serve two purposes. One is charitable, to protect open space from development; the other is practical, to preserve the land in productive agricultural use.
Gentry, Paige Madeline
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Procedure for conclusion of EU treaties with third states and international organizations [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2018
After the Lisbon Treaty has entered into force, the process of concluding treaties between the EU and third countries or international organizations has sustained significant changes.
Radivojević Zoran   +1 more
doaj  

Biochar Enhances Nitrous Oxide Reduction in Acidic but Not in Near-Neutral pH Soil

open access: yesSoil Systems, 2019
We quantified nitrous oxide (N2O) fluxes and total denitrification (N2O + N2) in an acidic (Ferralsol) and a near-neutral pH soil (Cambisol) to determine whether biochar’s alkalinization effect could be the mechanism inducing potential reductions ...
Engil Isadora Pujol Pereira   +4 more
doaj   +1 more source

Cunningham v. California [PDF]

open access: yes, 2007
In Cunningham v. California, the United States Supreme Court voted 6-3 to invalidate California\u27s determinate sentencing law ( DSL ) as violative of the Sixth and Fourteenth Amendments. The Court held that, notwithstanding the California Supreme Court\
Raab, Christopher P.
core   +1 more source

Does Article V Restrict the States to Calling Unlimited Conventions Only?—A Letter to a Colleague [PDF]

open access: yes, 1978
From time to time, various state legislatures have adopted resolutions designed to require Congress to call a limited convention in which one or another possible amendments to the Constitution might be proposed.
Van Alstyne, William W.
core   +3 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

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