Results 191 to 200 of about 3,471 (217)

Evaluation on absorption risks of amentoflavone after oral administration in rats

Biopharmaceutics & Drug Disposition, 2021
AbstractThe present study was aimed to systemically assess the absorption risks of amentoflavone (AMF). Physicochemical properties of AMF were evaluated using in vitro assays including water solubility and stability in both simulated gastric and intestinal fluids, as well as logD, pka and permeability studies in a monolayer Caco‐2 model.
Hui Qiu, Zhengbing Guo, Qian Xu, Shengfang Mao, Wenming Wu   +4 more
openaire   +2 more sources

Vasorelaxation by Amentoflavone Isolated fromSelaginella tamariscina

Planta Medica, 2004
In the courses of in vitro screening for the vasorelaxant effect of the various extracts from medicinal plants, an ethyl acetate-soluble extract of Selaginella tamariscina was found to exhibit distinctive vasorelaxant activity. Further purifications of the extract as guided by in vitro vasorelaxant assay afforded an active biflavonoid, amentoflavone ...
Dae Gill, Kang, Ming Hao, Yin, Hyuncheol, Oh, Dae Ho, Lee, Ho Sub, Lee   +4 more
openaire   +2 more sources

Semisynthetic preparation of amentoflavone: A negative modulator at GABAA receptors

Bioorganic & Medicinal Chemistry Letters, 2003
Amentoflavone is found in a number of plants with medicinal properties, including Ginkgo biloba and Hypericum perforatum (St. John's Wort). We have developed a rapid and economic semi-synthetic preparation of amentoflavone from biflavones isolated from autumnal Ginkgo biloba leaves.
Jane R, Hanrahan, Mary, Chebib, Neil L M, Davucheron, Belinda J, Hall, Graham A R, Johnston   +4 more
openaire   +2 more sources

Amentoflavone, a novel cyanobacterial killing agent from Selaginella tamariscina

Journal of Hazardous Materials, 2020
Harmful cyanobacterial bloom (HCB) by Microcystis aeruginosa is increasingly becoming a serious concern to the environment and human health alike. Currently, many physical, chemical, and biological controls are underway to eliminate HCB, but natural chemicals are rarely used.
Jaebok Lee, Minkyung Kim, Sang Eun Jeong, Hye Yoon Park, Che Ok Jeon, Woojun Park   +5 more
openaire   +2 more sources

The structure of WI3, the first optically active biflavone of the amentoflavone series

Experientia, 1969
Araucaria cookii donne les premieres bisflavones optiquement actives de la serie des amentoflavones. Une analyse complete des spectra de RNM des substances de cette serie a ete faite. Les deplacements methoxyliques induits par le solvant s'ajoutent aux resultats de l'analyse de RNM et les confirment.
A. Pelter, R. Warren, M. Ilyas, J. N. Usmani, S. P. Bhatnagar, R. H. Rizvi, M. Ilyas, W. Rahman   +7 more
openaire   +2 more sources

Apigenin and amentoflavone glycosides in the psilotaceae and their phylogenetic significance

Phytochemistry, 1978
Abstract Documentation of amentoflavone O -glucosides as the predominant flavonoid glycosides in both genera of the Psilotaceae clearly distinguishes this family from all other families of vascular plants. Psilotum and Tmesipteris also possess apigenin C - and O -glycosides as common flavonoid types.
James W. Wallace, Kenneth R. Markham
openaire   +1 more source

Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases

Chemico-Biological Interactions, 2018
Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are rarely reported. In this study, the inhibitory effects of AMF on
Xia, Lv, Jian-Bin, Zhang, Xin-Xin, Wang, Wen-Zhong, Hu, Yu-Sheng, Shi, Shu-Wen, Liu, Da-Cheng, Hao, Wei-Dong, Zhang, Guang-Bo, Ge, Jie, Hou, Ling, Yang   +10 more
openaire   +2 more sources

Transport of Amentoflavone Across the Blood-Brain Barrierin vitro

Planta Medica, 2002
The biflavone amentoflavone is an ingredient of Hypericum perforatum L. (Clusiaceae), a plant which is widely used for the treatment of mild to moderate depression. Amentoflavone inhibits the binding of flumazenil to the benzodiazepine binding site of the GABA A -receptor (IC(50) = 14.9 nM).
Gutmann H, Bruggisser R, Schaffner W, Bogman K, Botomino A, Drewe J   +5 more
openaire   +3 more sources

Amentoflavone protects the hematopoietic system of mice against γ-irradiation

Archives of Pharmacal Research, 2019
Some flavonoids have been shown to exhibit good antioxidant activity and protect mice from damage induced by radiation. Amentoflavone (AMF), a biflavonoid derived from the traditional herb-Selaginella tamariscina, has been reported to have antioxidant properties.
Xinyan, Qu, Qingjun, Li, Xiaojuan, Zhang, Zhaofen, Wang, Shengqi, Wang, Zhe, Zhou   +5 more
openaire   +2 more sources

Unraveling Amentoflavone's Therapeutic Potential in Alzheimer's Disease: A Preclinical Assessment

Combinatorial Chemistry & High Throughput Screening
Abstract: Alzheimer’s disease is one of the neurodegenerative diseases which causes cognition deficit. There are currently few medications available to treat Alzheimer's disease, even though researchers have devoted a great deal of time studying the condition and offering many benefits.
Sushma Singh, Neetu Agrawal, Ahsas Goyal
openaire   +2 more sources