Results 91 to 100 of about 2,676,862 (300)

Tras las huellas de Pierre Menard. "El Quijote" en el microrrelato hispanoamericano [PDF]

open access: yesParole Rubate, 2013
Some of the characteristic traits of short fiction, such as allusion, ellipsis and intertextuality, make Don Quixote a privileged book inasmuch as it achieves the necessary dialogue between writing and reading.
Rosa Pellicer
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Impact of the NeighborWorks America Catalytic Grant Program [PDF]

open access: yes, 2017
Over an 18-month period, NeighborWorks America ran a program through its Community Initiative Department called the Catalytic Grant Program (CGP).CGP was inspired by Community Initiatives' mission to support efforts to build vibrant local communities ...
NeighborWorks America
core  

Diasporada Sünni ve Şii Kimliklerin Silikleştiği Mezheplerüstü Yaklaşıma Bir Örnek Olarak Amerikan “Make Space” Topluluğu

open access: yesTurkish Journal of Shiite Studies
Amerika’da İslam’ın tarihi 17. yüzyılda Afrika’dan köle olarak getirilen Müslümanlarla başlamıştır. Müslümanlar geldikleri bu yeni ülkenin çok dilli, çok kültürlü “çoğulcu” yapısının etkisiyle temelde Sünni-Şii ayrışmasına dayanan yerel tartışmalarını bu
Halide Rumeysa Küçüköner
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Report on President Hosni Mubarak's meeting on conflict between Europe and United States of America

open access: yes, 1993
تقرير عن لقاء الرئيس المصري حسني مبارك مع مجموعة من المسؤليين المصريين ناقش خلاله الصراع التجاري بين أوروبا والولايات المتحدة الأمريكية والإجراءات الأخيرة التي حذرت الولايات المتحدة من إتخاذها في حالة استمرار مواقف تجارية معين لأوروبا الغربية.
Voice of America, Egypt
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Report on trip to Voice of America broadcasting station in Miami

open access: yes
تقرير قام به مدير مكتب برنامج صوت أمريكا، إبراهيم عابدين، حول زيارته لإحدى محطات الإرسال التابعة لإذاعة صوت أمريكا بمدينة ميامي في الولايات المتحدة.A report by Ibrahim Abdeen, Director of the Voice of America office, in which he discusses his visit to ...
Voice of America, Egypt
core  

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