Reducing frailty in frail people with multiple sclerosis: Feasibility of a 6-week multimodal exercise training program. [PDF]
Zanotto T +10 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Implementing the Lung Donor (LUNDON) acceptability score in U.S. donor management and transplant decision-making: A multi-aim, mixed-methods protocol. [PDF]
Rossetti NE +20 more
europepmc +1 more source
DECLINING MOUNTAIN SNOWPACK IN WESTERN NORTH AMERICA
P. Mote +3 more
semanticscholar +1 more source
Approaching September 11, 2002: will America, should America, can America \u201cdo everything alone\u201d [PDF]
Job, Cvijeto
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Reframing West Nile Virus in Latin America: From Enzootic Evidence to Human Risk-Surveillance Gaps and One Health Actions. [PDF]
Izquierdo-Condoy JS +8 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Challenges and Opportunities for Improved Tuberculosis and HIV Prevention in South America. [PDF]
Quispe-Juli CU +9 more
europepmc +1 more source
Changes toward Earlier Streamflow Timing across Western North America
I. Stewart, D. Cayan, M. Dettinger
semanticscholar +1 more source

