Research and resources in North American studies : plus ca change, plus c'est la même chose ; sixth scientific symposium Frankfurt – 6. Wissenschaftliches Symposium Frankfurt, Saturday, 7 October 2006, panel 4, 9:45 – 11:00 a.m. [PDF]
, 2006 Large American research libraries have been acquiring - by purchase and by lease - huge multi-disciplinary electronic collections of primary and secondary source materials.
Pankake, Marcia
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
SALT Equalizer, Vol. 2013, Issue 1
, 2013 Contents of This Issue: Survey Information and Methodology, at 1. 2012-13 SALT Salary Survey, at 1. About SALT and SALT Membership, at 3. Survey Instrument, at 4.
Society of American Law Teachers
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Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
American Orientalism and Cosmopolitan Mixed Race: Early Asian American Mixed Race in the American Literary Imagination [PDF]
, 2012 This paper offers and initial examination of representations of Asian American mixed race during the long period of Asian exclusion and enforced anti-miscegenation when racial mixing was legally proscribed. I argue that this literature must be understood
Poulsen, Melissa Eriko
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Proverbium, 2012 This article is a much longer version of a keynote address that I delivered at the “Colloque International de Parémiologie” on July 2, 2011, at the University of Paris-Diderot, at Paris, France.
Wolfgang Mieder
doaj