Results 181 to 190 of about 17,061,900 (337)
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Perspectives of stress and coping among older, college-educated African American women: a constructivist grounded theory study. [PDF]
Coats JV, Sanders Thompson VL.
europepmc +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
A dataset of whole-genome sequencing and genomic variants for the American Shad, <i>Alosa sapidissima,</i> from the Neuse River, North Carolina. [PDF]
Adams-Herrmann ES +5 more
europepmc +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
AABA Task Force on the Ethical Study of Human Remains Recommendations: Proposal for the Management and Oversight of Community Partnership and Ethical Stewardship of Human Remains. [PDF]
Auerbach BM +11 more
europepmc +1 more source

