Results 61 to 70 of about 15,375,091 (267)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Understanding North American curriculum reforms through theory of rationality [PDF]
Revista de Știinţe EducaţieiThe present study aims on the one hand to analyze North American curriculum reforms with a focus on the twentieth century, and on the other hand it aims to demonstrate the implications of Weberian rationality theory for century-specific curriculum ...
Dan-Laurențiu CARDAȘ-RĂDUȚA
doaj +1 more source
Inter-American Development Bank Sustainability Report 2014 [PDF]
, 2015 This report highlights the Inter-American Development Bank\u27s sustainability performance in 2014, both in achieving institutional sustainability investment and safeguards targets, as well as through a series of stories about the projects it is ...
Inter-American Development Bank
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Biography of Ele "Tony" Baker (1944-2012)
Journal of Lithic Studies, 2014 A short biography of Tony Baker.
Robert Patten
doaj +1 more source
Inter-American Development Bank Annual Report 2018: Financial Statements
, 2019 This report is the second of two volumes which together constitute the Inter-American Development Bank\u27s 2018 Annual Report. This report contains the management\u27s discussion and analysis of the Bank\u27s ordinary capital and financial ...
Inter-American Development Bank
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Inter-American Development Bank Cultural Center Information Bulletin: No. 123
, 2011 This bulletin announces the opening of the exhibition "New Visions: A Selection of the Latest Acquisitions from the IDB Art Collection, 2008-2011". This exhibition is part of the 19th anniversary celebrations of the Inter-American Development Bank (IDB ...
Inter-American Development Bank
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The Dilemma of Being American as a Consequence of Ethnic Segregation in Toni Morrison's Beloved
Rainbow: Journal of Literature, Linguistics and Culture, 2019 Slavery was a central institution in American society and was accepted as normal and applauded as a positive thing by many white Americans. America was full of Negro slaves when there were many injustice actions done by white people to black people ...
Novia Sekar Ayuningtyas +1 more
doaj +1 more source