Results 41 to 50 of about 7,997 (209)

Disseminated American cutaneous leishmaniasis in a patient with AIDS [PDF]

Memórias do Instituto Oswaldo Cruz, 1987
Chez un homme de 57 ans marie, vivant au sein de sa famille dans de bonnes conditions l'examen clinique montre de nombreuses papules ou nodules cutanes erythemateux, non ulceres sur la face, le thorax et les membres inferieurs, de diametre variable. Le SIDA aurait ete acquis par contact heterosexuel lors d'un voyage.
Coura, J. Rodrigues, Galvão-Castro, B., Grimaldi Junior, G.   +2 more
openaire   +4 more sources

The sandfly vectors and epidemiology of cutaneous leishmaniasis in the Landazury Focus, Colombia. [PDF]

This thesis describes a comprehensive cohort study of cutaneous leishmaniasis (CL) in a population of 2,704 followed over a period of 19 months, in the Opon focus, Landazury, Santander, Colombia.
Munoz-Mantilla, Gerardo
core   +1 more source

Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]

, 2005
BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Davies, C.R., Reithinger, R, Quinnell, RJ, Quinnell, R.J., Bismullah, M, Davies, CR, David, J.R., Reithinger, R., Mohsen, M., Wahid, M., Bismullah, M., Wahid, M, David, JR, Kolaczinski, J., Kolaczinski, J, Mohsen, M   +15 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

American tegumentary leishmaniasis: epidemiological and molecular characterization of prevalent Leishmania species in the State of Tocantins, Brazil, 2011-2015

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Determination of the epidemiological profile of the American tegumentary leishmaniasis (ATL) and identification of Leishmania species that are prevalent in the State of Tocantins were carried out through a retrospective and descriptive study based on ...
Carina Scolari Gosch, Cálita Pollyanna Marques, Bruna Silva Resende, Joandson dos Santos Souza, Ray Ameida da Silva Rocha, Deyse Sabrinne Souza Lopes, Marcelo Scolari Gosch, Fátima Ribeiro Dias, Miriam Leandro Dorta   +8 more
doaj   +1 more source

Efficacy of Miltefosine for the Treatment of American Cutaneous Leishmaniasis [PDF]

The American Society of Tropical Medicine and Hygiene, 2010
Miltefosine is an oral agent used for cutaneous leishmaniasis treatment. An open-label, randomized, phase III clinical trial was carried out in the Colombian army population. Miltefosine, 50 mg capsule was taken orally three times per day for 28 days (N = 145) or meglumine antimoniate, 20 mg/kg body weight per day for 20 days by intramuscular injection
Iván, Vélez, Liliana, López, Ximena, Sánchez, Laureano, Mestra, Carlos, Rojas, Erwin, Rodríguez   +5 more
openaire   +2 more sources

Recombinant LPG3 Protein From Leishmania chagasi as an Antigen for the Diagnosis of Canine Visceral Leishmaniasis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins, Anna Cláudia Alves de Souza, Bianca Meireles Miranda, Ronny Francisco de Souza, Daniel Silva Sena Bastos, Neverton José Silva Ferreira, Tiago Antônio de Oliveira Mendes, Celeste da Silva Freitas de Souza, George Luiz Lins Machado‐Coelho, Maria Terezinha Bahia, Leandro Licursi de Oliveira, Juliana Lopes Rangel Fietto, Eduardo de Almeida Marques‐da‐Silva   +12 more
wiley   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Epidermal Compromise in American Cutaneous Leishmaniasis

Journal of Investigative Dermatology, 1992
In American cutaneous leishmaniasis (ACL), Leishmania parasites enter the epidermis of the host via the bite of infected sandflies. Immune responses against the parasite vary from "effective" in localized (LCL) to a state of "selective anergy" in diffuse (DCL) cutaneous leishmaniasis, whereas the intermediate muco-cutaneous form (MCL) is characterized ...
Cáceres-Dittmar, Gisela, Sánchez, Martin A, Oriol, Olivia, Kraal, Georg, Tapia, Felix J   +4 more
openaire   +2 more sources

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source