Results 41 to 50 of about 1,329,284 (283)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Tra razzismo "scientifico" e razzismo politico
Rivista di Storia dell'Educazione, 2019 Come si arrivò all'emanazione delle leggi razziali nell'Italia fascista del 1938? Perché tra le istituzioni in cui vennero applicate più rigorosamente vi fu proprio la scuola?
David Salomoni
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Reassessing the Past: Memory and Identity in Toni Morrisonʼs Home
Filolog, 2021 Toni Morrison’s superior literary oeuvre reconsiders the American past by introducing memories of subjects who have been ignored or misrepresented in official history, with particular attention to their identity construction.
Ksenija M. Kondali, Sandra V. Novkinic
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Scientific Reports, 2020 The ‘Out of India’ hypothesis is often invoked to explain patterns of distribution among Southeast Asian taxa. According to this hypothesis, Southeast Asian taxa originated in Gondwana, diverged from their Gondwanan relatives when the Indian subcontinent
Stephanie F. Loria, Lorenzo Prendini
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
HOW AN AUTHENTIC SCIENCE COURSE BECAME DIGITAL AND ONLINE DURING THE COVID-19 PANDEMIC
Imagens da EducaçãoThis paper describes the conditions for teaching students and teacher-residents in the autumn of 2020 when professors in many countries needed to implement remote teaching.
Maritza Bentham Macdonald +1 more
doaj +1 more source
Vanport, Oregon: The Long History of an Ephemeral City
Iperstoria, 2022 On Memorial Day 1948, the Columbia River achieved what neither the Portland Housing Authority nor the city government had been able to do, i.e. to end the short history of Vanport, Oregon. Vanport had been created in 1942 as a huge public housing project
Uwe Lübken
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source