Results 71 to 80 of about 5,205,295 (314)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Bratt\u27s By the Vision of Another World: Worship in American History (Book Review)
, 2014 A Review of By the Vision of Another World: Worship in American History, edited by James D. Bratt. Grand Rapids, MI: Eerdmans, 2012. 213 pp. $25.00.
Avery, Joshua M
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Gene expression supports a single origin of horns and antlers in hoofed mammals
Communications BiologyHorns, antlers, and other bony cranial appendages of even-toed hoofed mammals (ruminant artiodactyls) challenge traditional morphological homology assessments.
Zachary T. Calamari, John J. Flynn
doaj +1 more source
, 2019 Marshall is a towering and inspirational figure in the history of American constitutional law. He changed American life forever and unquestionably for the better.
Post, Robert
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The role of flourishing in the STEM trajectories of emerging adults
Frontiers in EducationWe focus on the use of flourishing as a new measure in studies of pathways in STEM (science, technology, engineering, and mathematical) fields. While the concept of flourishing is promising, the concept may need careful interrogation to ensure it takes ...
Karen Hammerness +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
ZooKeys, 2018 An unusual and well-preserved fossil staphylinid is described and figured from a single specimen in Upper Cretaceous Burmese amber. Gollandia planata gen. et sp. n. is tentatively placed in the extant oxyteline tribe Coprophilini, although it lacks a few
György Makranczy +2 more
doaj +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source