Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Non-Immigrant Labor Policy in the United States [PDF]
, 1982 The employment of foreign workers as a supplement to the domestic labor force has been a recurrent public policy issue throughout much of the history of the United States.
Briggs, Vernon M. , Jr.
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FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
A study of the Central American Common Market [PDF]
, 1965 In the history of the Central American Republics many attempts at union, either political or economic or both, have been made and all have failed. Presently, these same countries are united economically once again as the Central American Common Market.
Harnad, Paul K., Olsen, Robert M.
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
African studies libraries: background to U.S. organization and initiatives and prospects for international cooperative projects : paper delivered at the German – North American resources project conference, 5 – 7 October 2006 ; [Vortrag am 6th Frankfurt scientific symposium, GNARP und wie sie die Welt sieht: Aussichten transatlantischer Partnerschaft im digitalen Zeitalter: 5.10.2006 - 7.10.2006] [PDF]
, 2006 The paper will provide a brief background to the history of the organization and cooperative efforts of African studies librarians in the United States including their efforts at international cooperation.
Easterbrook, David L.
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Reading the recent monetary history of the U.S., 1959-2007 [PDF]
The authors report the results of the estimation of a rich dynamic stochastic general equilibrium model of the U.S. economy with both stochastic volatility and parameter drifting in the Taylor rule.
Jesus Fernández-Villaverde +2 more
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An Overview of Collective Bargaining in the United States [PDF]
, 2014 [Excerpt] American history reflects a long cycle of trade union decline and growth. Analysts routinely predict the death of the labor movement. (Yeselson 2012).
Compa, Lance A
core +1 more source