Results 141 to 150 of about 29,634 (258)

A first in disease trial of the safety, tolerability, and anti‐seizure effects of ES‐481 in drug‐resistant epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives ES‐481 is a novel potent and selective antagonist of TARP‐y8‐dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES‐481 as an add‐on anti‐seizure medication (ASM) in adults with drug‐resistant epilepsy (DRE). Methods This was a Phase 2A double‐blind,
Emma C. Foster, Lyn Millist, Jack Germaine, Stephanie Chamorro, Caitlin Roberts, John‐Paul Nicolo, Sean Hosking, Piero Perucca, Saul Mullen, Heather Robinson, Rebecca Wharrie, Brittany Walsh, David Reutens, Kimberley Irwin, Hao Zeng, Robert Niecestro, Terence J. O'Brien   +16 more
wiley   +1 more source

Commentaires sur « Community in Native America: The Circle and the Sioux » de Raymond J. DeMallie

Nuevo mundo - Mundos Nuevos, 2017
doaj   +1 more source

Trends in alcohol-associated liver disease mortality rates in American Indians and Alaskan Natives. [PDF]

BMC Public Health
Zafar Y, Dodd IME, Iqbal AZ, Manzoor L, Iqbal NZ, Dodd KD, Petrasek J.   +6 more
europepmc   +1 more source

The 2025 Kamchatka Earthquake and Tsunami: Cascading Impacts and Risks to Japan

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT On July 29th, 2025, a large earthquake (Mw 8.8) occurred near the Kamchatka Peninsula. This event caused a tsunami that reached Japan's Pacific coast, even though the source was far away. In this study, we analyze the characteristics of earthquakes and tsunamis and discuss how they relate to the recurrence possibility and risk in Japan.
Ampan Laosunthara, An‐Chi Cheng, Yo Fukushima, Yoshinori Shigihara, Natt Leelawat, Anawat Suppasri, Fumihiko Imamura   +6 more
wiley   +1 more source

Traumatic brain injury among American indians/alaska natives in the united states: a comprehensive systematic review of the literature. [PDF]

Neurosurg Rev
Seltzer LA, Fouda MA, Pannullo SC.
europepmc   +1 more source

Multi‐Hazard Shaking‐Tsunami Fatality Risk Estimation for Coastal Communities

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT This study develops a multi‐hazard fatality risk model for a coastal community (Tofino) on Vancouver Island, Canada, subjected to earthquake‐tsunami threats from the Cascadia subduction megathrust events. The model incorporates variable population distributions and uncertain fatality rate models, in addition to other key model components, such
Katsuichiro Goda
wiley   +1 more source

Carotid artery atherosclerosis, MRI-defined structural brain abnormalities, and cognitive performance in elderly American Indians: The Strong Heart Study. [PDF]

Front Epidemiol
Ali T, Buchwald D, Shibata D, Roman MJ, Verney S, Howard BV, Umans J, Cole S, West C, Zhang Y, Reese J, Rhoades DA, O'Leary M, Longstreth WT, Fretts A, Suchy-Dicey A.   +15 more
europepmc   +1 more source

Glucose and Loss of Control Eating: Evidence From Naturalistic Assessment After Roux‐en‐Y Gastric Bypass

European Eating Disorders Review, EarlyView.
ABSTRACT Objective While loss of control (LOC) eating is associated with poor outcomes following metabolic and bariatric surgery (MBS), the mechanisms driving it are less understood. This study used momentary, naturalistic data to examine glucose as a biological correlate of LOC eating after Roux‐en‐Y gastric bypass (RYGB).
Gail A. Kerver, Kristine J. Steffen, Debra L. Safer, Glen Forester, David B. Sarwer, Stephen A. Wonderlich, Scott G. Engel   +6 more
wiley   +1 more source

The Importance of Considering Personal Recovery for Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Definitions of recovery from eating disorders (EDs) have traditionally emphasised symptom reduction and functional restoration. However, growing research highlights the importance of integrating personal recovery, defined by self‐acceptance, autonomy, and psychological wellbeing.
Andrew Allen, Maddison Tunstall, Catherine Houlihan, Kay Pozzebon, Daniel B. Fassnacht, Kathina Ali   +5 more
wiley   +1 more source

Urinary selenium, cranial MRI, and cognitive function in American Indians: The Strong Heart Study. [PDF]

Environ Res
Williams SC, Navas-Acien A, Goessler W, Verney SP, Erdei E, Buchwald D, Suchy-Dicey A, Best LG.   +7 more
europepmc   +1 more source